What is the ideal dose and power output of low-level laser therapy (810 nm) on muscle performance and post-exercise recovery? Study protocol for a double-blind, randomized, placebo-controlled trial

Trials

Ernesto Cesar Pinto Leal-Junior⁴  Jan Magnus Bjordal²  Paulo de Tarso Camillo de Carvalho⁴  Ivo de Oliveira Aleixo Junior⁴  Larissa Aline Santos⁴  Gianna Móes Albuquerque Pontes³  Paulo Roberto Vicente de Paiva³  Vanessa dos Santos Grandinetti³  Fernanda Colella Antonialli⁴  Thiago De Marchi¹  Adriane Aver Vanin⁴  Adriano Rodrigues de Oliveira³ 

[1] Sports Medicine Institute, University of Caxias do Sul, Rua Francisco Getulio Vargas 1130, Caxias do Sul, RS 95070-560, Brazil;Physiotherapy Research Group, Faculty of Medicine and Dentistry, University of Bergen, Kalfarveien 31, Bergen 5020, Norway;Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235, São Paulo, SP 01504-001, Brazil;Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235, São Paulo, SP 01504-001, Brazil

关键词: Exercise;    Phototherapy parameters;    Skeletal muscle recovery;    Skeletal muscle fatigue;    Low-level laser therapy;   

Others  :  807356
DOI  :  10.1186/1745-6215-15-69

 received in 2013-10-13, accepted in 2014-02-11,  发布年份 2014

【 摘 要 】

Background

Recent studies involving phototherapy applied prior to exercise have demonstrated positive results regarding the attenuation of muscle fatigue and the expression of biochemical markers associated with recovery. However, a number of factors remain unknown, such as the ideal dose and application parameters, mechanisms of action and long-term effects on muscle recovery. The aims of the proposed project are to evaluate the long-term effects of low-level laser therapy on post-exercise musculoskeletal recovery and identify the best dose andapplication power/irradiation time.

Design and methods

A double-blind, randomized, placebo-controlled clinical trial with be conducted. After fulfilling the eligibility criteria, 28 high-performance athletes will be allocated to four groups of seven volunteers each. In phase 1, the laser power will be 200 mW and different doses will be tested: Group A (2 J), Group B (6 J), Group C (10 J) and Group D (0 J). In phase 2, the best dose obtained in phase 1 will be used with the same distribution of the volunteers, but with different powers: Group A (100 mW), Group B (200 mW), Group C (400 mW) and Group D (0 mW). The isokinetic test will be performed based on maximum voluntary contraction prior to the application of the laser and after the eccentric contraction protocol, which will also be performed using the isokinetic dynamometer. The following variables related to physical performance will be analyzed: peak torque/maximum voluntary contraction, delayed onset muscle soreness (algometer), biochemical markers of muscle damage, inflammation and oxidative stress.

Discussion

Our intention, is to determine optimal laser therapy application parameters capable of slowing down the physiological muscle fatigue process, reducing injuries or micro-injuries in skeletal muscle stemming from physical exertion and accelerating post-exercise muscle recovery. We believe that, unlike drug therapy, LLLT has a biphasic dose–response pattern.

Trial registration

The protocol for this study is registered with the Protocol Registry System, ClinicalTrials.gov identifier NCT01844271.

【 授权许可】

   
2014 de Oliveira et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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