Successful treatment of paraneoplastic hypercalcemia in a patient with giant condyloma acuminatum: a case report

Journal of Medical Case Reports

Martin Görner¹  Peter Hirnle³  Mathias Löhnert²  Frauke Müller¹  Thomas Linnemann¹ 

[1] Department of Hematology and Oncology, Academic Teaching Hospital Bielefeld, Teutoburger Str. 50, Bielefeld 33604, Germany;Department of Surgery and Coloproctology, Academic Teaching Hospital Bielefeld Rosenhöhe, An der Rosenhöhe 27, Bielefeld 33647, Germany;Department of Radiotherapy, Academic Teaching Hospital Bielefeld, Teutoburger Strasse 50, Bielefeld 33604, Germany

关键词: Giant condyloma acuminatum;    Buschke-Löwenstein tumor;    Paraneoplastic hypercalcemia;   

Others  :  825065
DOI  :  10.1186/1752-1947-7-251

 received in 2013-03-26, accepted in 2013-08-29,  发布年份 2013

【 摘 要 】

Introduction

While paraneoplastic syndromes in patients with malignant and metastasizing tumors are common, they are rarely associated with skin tumors showing predominantly local growth patterns. This case report relates to a patient with giant condyloma acuminatum, also called Buschke-Löwenstein tumor, with paraneoplastic hypercalcemia, who was successfully treated with conservative treatment.

Case presentation

The patient in question is a 48-year-old German man with a giant periscrotal tumor. Before and during the therapy, two episodes of symptomatic hypercalcemia occurred, which were successfully treated by bisphosphonates, intravenous fluids and diuretics. No evidence of lytic bone affection was found.

Conclusions

Paraneoplastic hypercalcemia may occur in patients who have a Buschke-Löwenstein tumor. For patients, where surgery is not an option, established medical therapies like bisphosphonates may be useful in addition to diuretics and infusions.

【 授权许可】

   
2013 Linnemann et al.; licensee BioMed Central Ltd.

【 图 表 】

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