Two classes of nucleic acid translocation motors: rotation and revolution without rotation

Cell & Bioscience

Mario Vieweger²  Zhengyi Zhao²  Ian Grainge¹  Peixuan Guo² 

[1] Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan, 2308, Australia;Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA

关键词: DNA packaging;    Viral assembly;    DNA helicase;    DNA translocase;    Revolution;    Biomotor;    Hexameric ATPase;    Bacteriophage phi29;   

Others  :  1149330
DOI  :  10.1186/2045-3701-4-54

 received in 2014-09-11, accepted in 2014-09-11,  发布年份 2014

【 摘 要 】

Biomotors are extensively involved in biological processes including cell mitosis, bacterial binary fission, DNA replication, DNA repair, homologous recombination, Holliday junction resolution, RNA transcription, and viral genome packaging. Traditionally, they were classified into two categories including linear and rotation motors. In 2013, a third class of motor by revolution mechanism without rotation was discovered. In this issue of “Structure and mechanisms of nanomotors in the cells”, four comprehensive reviews are published to address the latest advancements of the structure and motion mechanism of a variety of biomotors in archaea, animal viruses, bacteria, and bacteriophages.

【 授权许可】

   
2014 Guo et al.; licensee BioMed Central Ltd.

【 图 表 】

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