Rheological and dielectric properties of different gold nanoparticle sizes

Lipids in Health and Disease

Magdy M Ghannam²  Mohsen M Mady¹  Mohamed Anwar K Abdelhalim² 

[1] Biophysics Department, Faculty of Science, Cairo University, 12613 Giza, Egypt;Department of Physics and Astronomy, College of Science, King Saud University, P.O. 2455, Riyadth 11451, Saudi Arabia

关键词: conductivity;    dielectric;    temperature;    size;    rheological parameters;    Gold nanoparticles;   

Others  :  1212426
DOI  :  10.1186/1476-511X-10-208

 received in 2011-11-06, accepted in 2011-11-11,  发布年份 2011

【 摘 要 】

Background

Gold nanoparticles (GNPs) have found themselves useful for diagnostic, drug delivery and biomedicine applications, but one of the important concerns is about their safety in clinical applications. Nanoparticle size has been shown to be an extremely important parameter affecting the nanoparticle uptake and cellular internalization. The rheological properties assume to be very important as it affects the pressure drop and hence the pumping power when nano-fluids are circulated in a closed loop. The rheological and dielectric properties have not been documented and identified before. The aim of the present study was to investigate the rheology and the dielectric properties of different GNPs sizes in aqueous solution.

Methods

10, 20 and 50 nm GNPs (Product MKN-Au, CANADA) was used in this study. The rheological parameters were viscosity, torque, shear stress, shear rate, plastic viscosity, yield stress, consistency index, and activation energy. These rheological parameters were measured using Brookfield LVDV-III Programmable rheometer supplied with temperature bath and controlled by a computer.

Results

The shear stress and shear rate of GNPs have shown a linear relationship and GNPs exhibited Newtonian behaviour. The GNPs with larger particle size (50 nm) exhibited more viscosity than those with smaller particle sizes (10 and 20 nm). Viscosity decreased with increasing the temperature for all the examined GNP sizes. The flow behaviour index (n) values were nearly ≤ 1 for all examined GNP sizes. Dielectric data indicated that the GNPs have strong dielectric dispersion in the frequency range of 20-100 kHz. The conductivity and relaxation time decreased with increasing the GNP size.

Conclusions

This study indicates that the GNP size has considerable influence on the viscosity of GNPs. The strong dielectric dispersion was GNP size dependent. The decrease in relaxation time might be attributed to increase in the localized charges distribution within the medium confirmed by the conductivity data. This study suggests that further experiments are required to be done after the administration of GNPs through different routes in rats in vivo.

【 授权许可】

   
2011 Abdelhalim et al; licensee BioMed Central Ltd.

【 图 表 】

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