Brucella ceti infection in dolphins from the Western Mediterranean sea

BMC Veterinary Research

Mariano Domingo⁸  José María Blasco⁵  Edgardo Moreno²  Rocio González-Barrientos¹  Esteban Chaves-Olarte³  Carlos Chacón-Díaz³  Montserrat Barberán⁵  Fernando Alegre⁷  Pilar M Muñoz⁵  Caterina Guzmán-Verri⁴  Lola Pérez⁶  Nazareth Ruiz-Villalobos⁴  Marcos Isidoro-Ayza⁶ 

[1] Ministerio de Agricultura y Ganadería, Laboratorio de Patología, Heredia, Costa Rica;Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica;Centro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica;Programa de Investigación en Enfermedades Tropicales, Escuela de Medicina Veterinaria, Universidad Nacional, Heredia, Costa Rica;CITA Gobierno de Aragón, Zaragoza, 50059, Spain;Departament de Sanitat i Anatomia Animal, Facultat de Veterinària, Universitat Autònoma de Barcelona (UAB), and Servei de Diagnòstic de Patologia Veterinària, Facultat de Veterinària, Universitat Autònoma de Barcelona (UAB), Bellaterra, Barcelona, 08193, Spain;Centre Fundación para la Conservación y Recuperación de Animales Marinos (CRAM), El Prat de Llobregat, Barcelona, Spain;Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Bellaterra, Cerdanyola del Vallès, Barcelona, 08193, Spain

关键词: Mediterranean sea;    Discospondylitis;    Neurobrucellosis;    Cetacean;    Brucella ceti;   

Others  :  1118993
DOI  :  10.1186/s12917-014-0206-7

 received in 2014-03-02, accepted in 2014-08-28,  发布年份 2014

【 摘 要 】

Background

Brucella ceti infections have been increasingly reported in cetaceans. Brucellosis in these animals is associated with meningoencephalitis, abortion, discospondylitis’, subcutaneous abscesses, endometritis and other pathological conditions B. ceti infections have been frequently described in dolphins from both, the Atlantic and Pacific Oceans. In the Mediterranean Sea, only two reports have been made: one from the Italian Tyrrhenian Sea and the other from the Adriatic Sea.

Results

We describe the clinical and pathological features of three cases of B. ceti infections in three dolphins stranded in the Mediterranean Catalonian coast. One striped dolphin had neurobrucellosis, showing lethargy, incoordination and lateral swimming due to meningoencephalitis, A B. ceti infected bottlenose dolphin had discospondylitis, and another striped dolphin did not show clinical signs or lesions related to Brucella infection. A detailed characterization of the three B. ceti isolates was performed by bacteriological, molecular, protein and fatty acid analyses.

Conclusions

All the B. ceti strains originating from Mediterranean dolphins cluster together in a distinct phylogenetic clade, close to that formed by B. ceti isolates from dolphins inhabiting the Atlantic Ocean. Our study confirms the severity of pathological signs in stranded dolphins and the relevance of B. ceti as a pathogen in the Mediterranean Sea.

【 授权许可】

   
2014 Isidoro-Ayza et al.; licensee BioMed Central Ltd.

【 图 表 】

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