Risk factors for incidence and persistence of disability in chronic major depression and alcohol use disorders: Longitudinal analyses of a population-based study

Health and Quality of Life Outcomes

José Luis Ayuso-Mateos²  Alarcos Cieza¹  Somnath Chatterji³  Francisco Félix Caballero²  María Cabello² 

[1] Disability and Rehabilitation Unit Coordinator, World Health Organization, Geneva, Switzerland;Instituto de Investigación Sanitaria Princesa (IP), La Princesa University Hospital, Madrid, Spain;Department of Health Statistics and Information Systems, World Health Organization, Geneva, Switzerland

关键词: Disability;    Alcohol use disorders;    Major depression;   

Others  :  1133912
DOI  :  10.1186/s12955-014-0186-0

 received in 2014-07-25, accepted in 2014-12-08,  发布年份 2014

【 摘 要 】

Background

Major depression and alcohol use disorders are risk factors for incidence of disability. However, it is still unclear whether a chronic course of these health conditions is also prospectively associated with incidence of disability. The aim of the present study was, first, to confirm whether chronic major depression (MD) and alcohol use disorders (AUD) are, respectively, risk factors for persistence and incidence of disability in the general population; and then to analyze the role of help-seeking behavior in the course of disability among respondents with chronic MD and chronic AUD.

Method

Data from two assessments in the National Epidemiologic Survey on Alcohol and Related Conditions were analyzed. Disability was measured by eight domains of the Short Form 12 Health Survey version 2 (SF-12). Generalized estimating equations and logistic regression models were run to estimate risk factors for persistence and incidence of disability, respectively.

Results

Analyses conducted on data from the US general population showed that chronic MD was the strongest risk factor for incidence and persistence of disability in the social functioning, emotional role and mental health domains. Chronic AUD were risk factors for incidence and persistence of disability in the vitality, social functioning, and emotional role domains. Within the group of chronic MD, physical comorbidity and help-seeking were associated with persistent disability in most of the SF-12 domains. Help-seeking behavior was also associated with incidence of problems in the mental health domain for the depression group. Regarding the AUD group, comorbidity with physical health problems was a strong risk factor for persistence of disability in all SF-12 domains. Help-seeking behavior was not related to either persistence or incidence of disability in the chronic alcohol group.

Conclusions

Chronic MD and chronic AUD are independent risk factors for persistence and incidence of disability in the US general population. People with chronic MD seek help for their problems when they experience persistent disability, whereas people with chronic AUD might not seek any help even if they are suffering from persistent disability.

【 授权许可】

   
2014 Cabello et al.; licensee BioMed Central.

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