Semi-automated left ventricular segmentation based on a guide point model approach for 3D cine DENSE cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance

Bruce S Spottiswoode³  Ernesta M Meintjes²  Frederick H Epstein⁴  Xiaodong Zhong¹  Daniel A Auger² 

[1]MR R&D Collaborations, Siemens Medical Solutions, Atlanta, GA, USA

[2]MRC/UCT Medical Imaging Research Unit, Department of Human Biology, University of Cape Town, Cape Town, South Africa

[3]Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL 60611, USA

[4]Departments of Radiology and Biomedical Engineering, University of Virginia, Charlottesville, VA, USA

关键词: Guide point modeling;    Segmentation;    DENSE;    Cardiovascular MR;   

Others  :  801902
DOI  :  10.1186/1532-429X-16-8

 received in 2013-02-05, accepted in 2013-12-03,  发布年份 2014

【 摘 要 】

Background

The most time consuming and limiting step in three dimensional (3D) cine displacement encoding with stimulated echoes (DENSE) MR image analysis is the demarcation of the left ventricle (LV) from its surrounding anatomical structures. The aim of this study is to implement a semi-automated segmentation algorithm for 3D cine DENSE CMR using a guide point model approach.

Methods

A 3D mathematical model is fitted to guide points which were interactively placed along the LV borders at a single time frame. An algorithm is presented to robustly propagate LV epicardial and endocardial surfaces of the model using the displacement information encoded in the phase images of DENSE data. The accuracy, precision and efficiency of the algorithm are tested.

Results

The model-defined contours show good accuracy when compared to the corresponding manually defined contours as similarity coefficients Dice and Jaccard consist of values above 0.7, while false positive and false negative measures show low percentage values. This is based on a measure of segmentation error on intra- and inter-observer spatial overlap variability. The segmentation algorithm offers a 10-fold reduction in the time required to identify LV epicardial and endocardial borders for a single 3D DENSE data set.

Conclusion

A semi-automated segmentation method has been developed for 3D cine DENSE CMR. The algorithm allows for contouring of the first cardiac frame where blood-myocardium contrast is almost nonexistent and reduces the time required to segment a 3D DENSE data set significantly.

【 授权许可】

   
2014 Auger et al.; licensee BioMed Central Ltd.

【 图 表 】

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