Laser Doppler Vibrometry measurements of human cadaveric tympanic membrane vibration

Journal of Otolaryngology-Head & Neck Surgery

Sumit K Agrawal³  Hanif M Ladak²  Seyed Alireza Rohani¹  Jason A Beyea⁴ 

[1] Biomedical Engineering Graduate Program, Western University, London, ON, Canada;Department of Electrical and Computer Engineering, Western University, London, ON, Canada;Schulich School of Medicine and Dentistry, Department of Otolaryngology - Head and Neck Surgery, Western University, 339 Windermere Road, P.O. Box 5339, London, ON, Canada;Department of Otolaryngology – Head and Neck Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada

关键词: Conductive hearing loss;    Tympanic membrane vibration;    Otosclerosis;    Incudo-stapedial joint separation;    Malleus head fixation;    Laser Doppler Vibrometry;   

Others  :  861890
DOI  :  10.1186/1916-0216-42-17

 received in 2012-11-20, accepted in 2013-01-06,  发布年份 2013

【 摘 要 】

Objective

To determine the feasibility of measuring tympanic membrane (TM) vibrations at multiple locations on the TM to differentiate normal eardrums from those with associated ossicular pathologies.

Design

Cadaveric human temporal bone study.

Setting

Basic science laboratory.

Methods

A mastoidectomy and facial recess approach was performed on four cadaveric temporal bones to obtain access to the ossicles without disrupting the TM. Ossicles were palpated to ensure normal mobility and an intact ossicular chain. Laser Doppler Vibrometry (LDV) measurements were then taken on all four TMs. LDV measurements were repeated on each TM following stapes footplate fixation, incudo-stapedial joint dislocation, and malleus head fixation.

Main outcome measures

LDV measurements of TM vibration at the umbo, the lateral process of the malleus, and in each of the four quadrants of the TM.

Results

The best signal-to-noise ratios were found between 2 and 4 kHz, at the umbo, the anterior superior quadrant, the anterior inferior quadrant, and the posterior inferior quadrant. Since our goal was to assess the ossicular chain, we selected the TM locations closest to the ossicular chain (the umbo and lateral process of the malleus) for further analysis. Differences could be seen between normals and the simulated ossicular pathologies, but values were not statistically significant.

Conclusions

LDV measurements are technically challenging and require optimization to obtain consistent measurements. This study demonstrates the potential of LDV to differentiate ossicular pathologies behind an intact tympanic membrane. Future studies will further characterize the clinical role of this diagnostic modality.

【 授权许可】

   
2013 Beyea et al; licensee BioMed Central Ltd.

【 图 表 】

【 参考文献 】

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