Prostatic paracoccidioidomycosis with a fatal outcome: a case report

Journal of Medical Case Reports

Moacir Fernandes de Godoy¹  Laísa Ferraz de Arruda²  Eduardo Maciel Narvaes³  Daniel Cernach Ayres³  José Germano Ferraz de Arruda³  Márcio Gatti³  Pedro Francisco Ferraz de Arruda³ 

[1] Cardiology and Cardiovascular Surgery Department, São José do Rio Preto Medical School, Av. Brigadeiro Faria Lima 5416, 15090-000, São José do Rio Preto, SP, Brazil;Medical Department, União das Faculdades dos Grandes Lagos, Unilago, Rua Dr. Eduardo Nielsem, 960 Jd. N. Aeroporto, 15030-070, São José do Rio Preto, SP, Brazil;Urology Department, São José do Rio Preto Medical School, Av. Brigadeiro Faria Lima 5416, 15090-000, São José do Rio Preto, SP, Brazil

关键词: prostatitis;    paracoccidioidomycosis;    Paracoccidioides brasiliensis;    Prostate;   

Others  :  1181193
DOI  :  10.1186/1752-1947-7-126

 received in 2012-12-03, accepted in 2013-03-28,  发布年份 2013

【 摘 要 】

Introduction

Paracoccidioidomycosis is a systemic mycosis in Latin America that can affect various organs. Few case reports of paracoccidioidomycosis affecting the prostate are found in the literature.

Case presentation

We present the case of a 79-year-old Caucasian man with a six-month history of irritative symptoms of the prostate (urgency, frequency and nocturia) and difficulty initiating urination that progressed to urinary retention and the use of a urinary catheter. The anatomopathological analysis of the transurethral resection of the prostate revealed chronic granulomatous prostatitis of fungal etiology (paracoccidioidomycosis) with extensive necrosis. The patient began treatment with itraconazole at a dose of 100mg/day for six months. Radiography of the thorax revealed bilaterally diffuse nodular reticular interstitial lesions. The patient progressed to respiratory failure and was sent to the intensive care unit, but suffered a cardiopulmonary arrest and was pronounced dead.

Conclusions

Due to the high incidence of paracoccidioidomycosis in countries like Brazil, urologists should suspect blastomycosis in all patients with symptoms of lower urinary obstruction with chronic abacterial prostatitis. Considering that paracoccidioidomycosis has the potential to affect various organs, following diagnosis, the treatment must be initiated as soon as possible.

【 授权许可】

   
2013 de Arruda et al.; licensee BioMed Central Ltd.

【 图 表 】

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Figure 2.

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