Hepatolithiasis associated with intrahepatic heterotopic pancreas: a case report and literature review

Diagnostic Pathology

Shu-Sen Zheng²  Wen Lu¹  Bei Wang²  Min Zhang²  Zhong-Quan Sun²  Zhi-Yong Yu² 

[1] Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310012, Zhejing Province, China;Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejing University School of Medicine, Hangzhou 310003, Zhejing Province, China

关键词: Biliary epithelia cells;    Metaplasia;    Hepatolithiasis;    Biliary tract;    Liver;    Heterotopic pancreas;   

Others  :  1219371
DOI  :  10.1186/s13000-015-0319-8

 received in 2015-02-01, accepted in 2015-06-10,  发布年份 2015

【 摘 要 】

Intrahepatic heterotopic pancreas is rarely reported in the literature. Here, we report a case of a 39-year-old male with intrahepatic heterotopic pancreas associated with primary cholesterol hepatolithiasis. Computed tomography (CT) scans revealed multiple cholesterol stones in intrahepatic bile ducts of the left lobe concomitant with intrahepatic cholangiectases. These observations were confirmed by magnetic resonance cholangiopaneretography (MRCP). The patient underwent transabdominal left hepatic lobectomy. Postoperative histological examination of the resected specimen showed pancreatic tissues distributed along the wall of the bile duct and composed of acinar cells and duct elements without islets of Langerhans, therefore strongly suggesting that the heterotopic pancreas occurred in response to chronic injury due to the primary cholesterol hepatolithiasis and was derived from the biliary epithelial cells.

【 授权许可】

   
2015 Yu et al.

【 图 表 】

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