期刊论文详细信息
Journal of Medical Case Reports
Non-invasive respiratory volume monitoring identifies opioid-induced respiratory depression in an orthopedic surgery patient with diagnosed obstructive sleep apnea: a case report
Edward George1  Christopher Voscopoulos3  Eamon Fleming2 
[1] Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston 02114, MA, USA;Respiratory Motion, 411 Waverley Oaks Rd #150, Waltham 02452, MA, USA;59 Hawk Crest Court, Roseville 95678, CA, USA
关键词: Respiratory volume monitoring;    Post-operative;    Opioid-induced respiratory depression;    Obstructive sleep apnea;    Non-invasive;    Minute ventilation;   
Others  :  1204623
DOI  :  10.1186/s13256-015-0577-9
 received in 2014-11-26, accepted in 2015-03-19,  发布年份 2015
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【 摘 要 】

Introduction

Obstructive sleep apnea and opioid-induced respiratory depression can unpredictably threaten respiratory competence in the post-anesthesia care unit. Current respiratory monitoring relies heavily on respiratory rate and oxygen saturation, as well as subjective clinical assessment. These assessments have distinct limitations, and none provide a real-time, objective, quantitative direct measurement of respiratory status. A novel, non-invasive respiratory volume monitor uses bioimpedance to provide accurate, quantitative measurements of minute ventilation, tidal volume and respiratory rate continuously in real time, providing a direct measurement of ventilation.

Case presentation

The case describes an orthopedic surgery patient (54-year-old Caucasian man, body mass index 33.7kg/m2) with diagnosed obstructive sleep apnea in whom the respiratory volume monitor data depicted persistent apneic behavior undetected by other monitoring. The monitor was able to detect a sudden reduction in minute ventilation after initial opioid administration in the post-anesthesia care unit. The patient had sustained low minute ventilation until discharge. Neither respiratory rate data from the hospital monitor nor oxygen saturation readings reflected the respiratory decompensation, remaining within normal limits even during sustained low minute ventilation.

Conclusions

The events of this case illustrate the limitations of current respiratory rate monitoring and pulse oximetry in the evaluation of post-surgical respiratory status. Our patient displayed stable respiratory rate and no evidence of desaturation, despite sustained low minute ventilation, and he received opioids in the post-anesthesia care unit despite already compromised ventilation. Because the available monitoring did not indicate the patient’s true respiratory status, he was treated with additional opioids, markedly increasing his risk for further respiratory decline.

【 授权许可】

   
2015 Fleming et al.; licensee BioMed Central.

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