Primary cardiac lymphoma: two cases and a review of literature

Journal of Cardiothoracic Surgery

Vytautas Sirvydis¹  Virgilijus Tarutis⁴  Nomeda Valeviciene²  Raimundas Meskauskas³  Kestutis Salcius¹  Karolis Jonavicius⁴ 

[1] Department of Cardiovascular Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania;Department of Radiology, Nuclear Medicine and Physics of Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania;National Centre of Pathology, Affiliate of Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania;Vilnius University Faculty of Medicine Centre of Cardiac Surgery, Santariskiu g. 2, Vilnius 08661, Lithuania

关键词: Large B cell lymphoma;    Heart tumour;    Primary cardiac lymphoma;   

Others  :  1232311
DOI  :  10.1186/s13019-015-0348-0

 received in 2014-12-16, accepted in 2015-10-28,  发布年份 2015

【 摘 要 】

Background

Primary cardiac lymphoma is one of the rarest tumours of the heart. It belongs to the extra-nodal non-Hodgkin’s lymphomas. The most common type of this tumour is diffuse large B cell lymphoma. Usually, right atrium and right ventricle are involved. This tumour is fatal unless diagnosed and treated in time. In this article two female patients who were diagnosed with primary cardiac lymphoma and treated at our clinic are described. The first patient went to remission after the treatment, while the second patient died. The goals of this article are to show the difficulties of diagnosing and treating this disease, the role of cardiac surgery in its treatment and to raise awareness of this disease.

Case reports

In this article two female patients who were diagnosed with primary cardiac lymphoma and treated at our clinic are described. The first patient went to remission after the treatment, while the second patient died.

Conclusions

Primary cardiac lymphoma is a very rare disease. At the moment the most effective treatment is chemotherapy. Palliative surgery may be necessary to correct hemodynamics when venous blood flow to the lungs is disturbed.

【 授权许可】

   
2015 Jonavicius et al.

【 图 表 】

Fig. 1.

Fig. 2.

Fig. 3.

【 参考文献 】

• [1]Johri A, Baetz T, Isotalo PA, Nolan RL, Sanfilippo AJ, Ropchan G. Primary cardiac diffuse large B cell lymphoma presenting with superior vena cava syndrome. Can J Cardiol. 2009; 25:e210-2.
• [2]Zhong L, Yang S, Lei K, Jia Y. Primary cardiac lymphoma: a case report and review of the literature. Chin-Ger J Clin Oncol. 2013; 12:43-5.
• [3]Jung YH, Woo IS, Ko YJ, Lee JH, Lim JW, Han CW. A case of primary cardiac lymphoma showing isolated central nervous system relapse. Clin Lymphoma Myeloma Leuk. 2014; 14:e31-3.
• [4]Chen K-W, Chang J-H, Yeh S-P, Lu C-R. Primary cardiac B-cell lymphoma with atrioventricular block and paroxysmal ventricular tachycardia. J Cardiothorac Surg. 2012; 7:70. BioMed Central Full Text
• [5]Rolla G, Bertero MT, Pastena G, Tartaglia N, Corradi F, Casabona R et al.. Primary lymphoma of the heart. A case report and review of the literature. Leuk Res. 2002; 26:117-20.
• [6]Nand S, Mullen GM, Lonchyna VA, Moncada R. Primary lymphoma of the heart. Prolonged survival with early systemic therapy in a patient. Cancer. 1991; 68:2289-92.
• [7]Coiffier B, Lepage E, Brière J, Herbrecht R, Tilly H, Bouabdallah R et al.. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002; 346:235-42.
• [8]Zaharia L, Gill PS. Primary cardiac lymphoma. Am J Clin Oncol. 1991; 14:142-5.
• [9]Curtsinger CR, Wilson MJ, Yoneda K. Primary cardiac lymphoma. Cancer. 1989; 64:521-5.
• [10]Petrich A, Cho SI, Billett H. Primary cardiac lymphoma. Cancer. 2011; 117:581-9.
• [11]Lee GY, Kim WS, Ko Y-H, Choi J-O, Jeon E-S. Primary cardiac lymphoma mimicking infiltrative cardiomyopathy. Eur J Heart Fail. 2013; 15:589-91.
• [12]Yoshihara S, Naito M, Tanioka F, Matsunaga M. A case of primary cardiac lymphoma: in vivo imaging and pathologic correlation. Eur Heart J Cardiovasc Imaging. 2013; jet051.
• [13]Khuddus MA, Schmalfuss CM, Aranda JM, Pauly DF. Magnetic resonance imaging of primary cardiac lymphoma. Clin Cardiol. 2007; 30:144-5.
• [14]Burling F, Devlin G, Heald S. Primary cardiac lymphoma diagnosed with transesophageal echocardiography–guided endomyocardial biopsy. Circulation. 2000; 101:e179-81.
• [15]Chin JY, Chung MH, Kim JJ, Lee JH, Kim JH, Maeng IH et al.. Extensive primary cardiac lymphoma diagnosed by percutaneous endomyocardial biopsy. J Cardiovasc Ultrasound. 2009; 17:141.
• [16]Jurkovich D, de Marchena E, Bilsker M, Fierro-Renoy C, Temple D, Garcia H. Primary cardiac lymphoma diagnosed by percutaneous intracardiac biopsy with combined fluoroscopic and transesophageal echocardiographic imaging. Catheter Cardiovasc Interv. 2000; 50:226-33.
• [17]Habertheuer A, Ehrlich M, Wiedemann D, Mora B, Rath C, Kocher A. A rare case of primary cardiac B cell lymphoma. J Cardiothorac Surg. 2014; 9:14. BioMed Central Full Text