Assessment of long-term quality of life after cavotricuspid isthmus ablation for typical atrial flutter

Health and Quality of Life Outcomes

José R González-Juanatey²  Xesús Alberte Fernández-López²  José Luis Martínez-Sande²  Francisco Gude¹  Javier García-Seara²  Pilar Cabanas-Grandío² 

[1] Epidemiology Department, University Clinical Hospital of Santiago de Compostela, Santiago de Compostela, Spain;Cardiology Department, University Clinical Hospital of Santiago de Compostela, Choupana, 15706 Santiago de Compostela, Spain

关键词: Quality of life;    Ablation;    Typical atrial flutter;   

Others  :  814994
DOI  :  10.1186/1477-7525-12-47

 received in 2013-09-16, accepted in 2014-03-19,  发布年份 2014

【 摘 要 】

Background

Cavotricuspid isthmus (CTI) ablation is the treatment of choice in preventing recurrences of typical atrial flutter (AFl). However, little is known about long-term quality of life (QoL) after CTI ablation.

Methods and results

From 01/2003 to 05/2005, 94 patients who consecutively underwent typical AFl ablation were included in the study. An SF-36 health questionnaire was self-administered before ablation and at follow-up. Transformed scores were calculated, adjusted for age and sex and then normalized and standardized for the Spanish population. Additionally, the minimal important differences (MID) were calculated to assess the smallest change in QoL that patients perceived as positive. A linear regression model was constructed to assess long-term QoL predictors. All SF-36 scales were lower than Spanish population scores. After a mean (SD) follow-up of 6.25 (0.5) years, all scales, except Bodily Pain, were higher than baseline. There was a significant difference for Physical Role (46.4 vs. 38.6, p < 0.001), Vitality (44.4 vs. 41.9, p = 0.038) and Mental Health (46.1 vs. 42.0, p = 0.001). However, only Physical Role achieved the criteria for MID. Recurrence of AFl, basal QoL, history of diabetes mellitus, atrial fibrillation and oral anticoagulation were predictors of long-term QoL.

Conclusion

CTI ablation provides a significant improvement in long-term QoL for the dimensions of Physical Role, Vitality and Mental Health, although the smallest positive change that patients perceive as positive was only observed for Physical Role. Previous diabetes mellitus, atrial fibrillation, oral anticoagulation, basal QoL and AFl recurrence were determinants of a worse long-term QoL.

【 授权许可】

   
2014 Cabanas-Grandío et al.; licensee BioMed Central Ltd.

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