Metabolic syndrome and menopause

Journal of Diabetes & Metabolic Disorders

Mojgan Asadi¹  Mostafa Qorbani²  Farnaz Nayebzadeh³  Zahra Jouyandeh¹ 

[1] Endocrine & Metabolism Research Center, Tehran University of Medical Science, Tehran, Iran;Department of Epidemiology & Biostatistics, School of Public Health Tehran University of Medical Sciences, Tehran, Iran;Tehran Women General Hospital, Tehran University of Medical Science, Tehran, Iran

关键词: Prevalence;    Metabolic syndrome;    Menopause;   

Others  :  807151
DOI  :  10.1186/2251-6581-12-1

 received in 2012-08-27, accepted in 2012-12-25,  发布年份 2013

【 摘 要 】

Background

The metabolic syndrome is defined as an assemblage of risk factors for cardiovascular diseases, and menopause is associated with an increase in metabolic syndrome prevalence. The aim of this study was to assess the prevalence of metabolic syndrome and its components among postmenopausal women in Tehran, Iran.

Methods

In this cross-sectional study in menopause clinic in Tehran, 118 postmenopausal women were investigated. We used the adult treatment panel 3 (ATP3) criteria to classify subjects as having metabolic syndrome.

Results

Total prevalence of metabolic syndrome among our subjects was 30.1%. Waist circumference, HDL-cholesterol, fasting blood glucose, diastolic blood pressure ,Systolic blood pressure, and triglyceride were significantly higher among women with metabolic syndrome (P-value<0.05). Our study shows high abdominal obesity and hypertension are the most prevalent components of metabolic syndrome. 15%, 13.3% and 1.8% of subjects had three, four and five criteria for metabolic syndrome, respectively. There was a significant relationship between number of components of metabolic syndrome and waist circumference.

Conclusions

Our study shows that postmenopausal status is associated with an increased risk of metabolic syndrome. Therefore, to prevent cardiovascular disease there is a need to evaluate metabolic syndrome and its components from the time of the menopause.

【 授权许可】

   
2013 Jouyandeh et al.; licensee BioMed Central Ltd.

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