Application of molecular imprinted polymer nanoparticles as a selective solid phase extraction for preconcentration and trace determination of 2,4-dichlorophenoxyacetic acid in the human urine and different water samples

Journal of Environmental Health Science Engineering

Seyed Jamaleddin Shahtaheri¹  Alireza Sedighi²  Hamid Sadeghi Abandansari³  Mohammad Behbahani³  Fariborz Omidi⁴ 

[1] Department of Occupational Health Engineering, School of Public Health and Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran;Department of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran;Department of Chemistry, Shahid Beheshti University, Tehran, Iran;Department of Occupational Health Engineering, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran

关键词: Urine and water samples;    Selective preconcentration;    2,4-dichlorophenoxyacetic acid;    Molecular imprinted polymer nanoparticles;   

Others  :  1175283
DOI  :  10.1186/s40201-014-0137-z

 received in 2013-12-25, accepted in 2014-10-29,  发布年份 2014

【 摘 要 】

A molecular-imprinted polymer nanoparticles (MIP-NP) for the selective preconcentration of 2,4-dichlorophenoxyacetic acid (2,4-D) is described. It was obtained by precipitation polymerization from methacrylic acid (the functional monomer), ethylene glycol dimethacrylate (the cross-linker), 2,2?-azobisisobutyronitrile (the initiator) and 2,4-D (the template molecule) in acetonitrile solution. The MIP-NPs were characterized by thermogravimetric analysis, and by scanning electron microscopy. Imprinted 2,4-D molecules were removed from the polymeric structure using acetic acid in methanol (15:85 v/v %) as the eluting solvent. The sorption and desorption process occur within 10 min and 15 min, respectively. The maximum sorbent capacity of the molecular imprinted polymer is 89.2 mg g^?1. The relative standard deviation and limit of detection for water samples by introduced selective solid phase extraction were 4.2% and 1.25 ?g L^?1, and these data for urine samples were 4.7% and 1.80 ?g L^?1, respectively. The method was applied to the determination of 2,4-D in the urine and different water samples.

【 授权许可】

   
2014 Omidi et al.; licensee BioMed Central Ltd.; licensee BioMed Central Ltd.

【 图 表 】

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