Risk factors for breast cancer in Iran: a case-control study

Breast Cancer Research

Ali Montazeri¹  Mariam Vahdaninia²  Mandana Ebrahimi² 

[1] Department of Public Health, University of Glasgow, Glasgow, Scotland;Iranian Centre for Breast Cancer, Tehran, Iran

关键词: risk factor;    Iran;    case-control;    breast cancer;   

Others  :  1118824
DOI  :  10.1186/bcr454

 received in 2002-01-12, accepted in 2002-06-20,  发布年份 2002

【 摘 要 】

Background

Iranian breast cancer patients are relatively younger than their Western counterparts. The objective of the present study was to investigate risk factors for breast cancer in Iranian women.

Method

A case-control study was conducted from April 1997 to April 1998 in Tehran, Iran. Demographical data and risk factor related information were collected using a short structured questionnaire. Odds ratios (ORs) and 95% confidence intervals (CIs) were derived from logistic regression analysis.

Results

In all, 286 women with breast cancer and 249 control women were interviewed. In multivariate analysis, only marital status (never married: OR 4.24, 95% CI 1.70-10.57 [P = 0.002]; widowed/divorced: OR 1.71, 95% CI 1.05-2.68 [P = 0.03]) and family history (positive family history of breast cancer: OR 2.95, 95% CI 1.15-7.59 [P = 0.02]) were associated with significantly increased risk for breast cancer.

Conclusion

The findings of the present study suggest that family history and marital status may have an impact on the incidence of breast cancer in Iranian women.

【 授权许可】

   
2002 Ebrahimi et al., licensee BioMed Central Ltd

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