European Journal of Medical Research | |
Magnetic resonance imaging and endorectal ultrasound for diagnosis of rectal lesions | |
Justyna Szumilo1 Iwonna Zelazowska-Cieslinska3 Marek Caban3 Agnieszka Mocarska3 Robert Klepacz1 Malgorzata Kolodziejczak2 Elzbieta Staroslawska3 Iwona Sudol-Szopinska4 Franciszek Burdan5 | |
[1] Department of Clinical Pathomorphology, Medical University of Lublin, 1 Ceramiczna Str., Lublin, 20-059, Poland;Department of Proctology, Hospital at Solec, 93 Solec Str., Warsaw, 00-382, Poland;St. John’s Cancer Centre, 7 Jaczewskiego Str., Lublin, 20-090, Poland;Department of Diagnostic Imaging, Second Faculty of Medicine, Medical University of Warsaw, 8 Kondratowicza Str., Warsaw, 03-242, Poland;Department of Human Anatomy, Medical University of Lublin, 4 Jaczewskiego Str., Lublin, 20-090, Poland | |
关键词: Anal cancer; Rectal cancer; Perianal fistula; Magnetic resonance; Endorectal ultrasonography; | |
Others : 1103392 DOI : 10.1186/s40001-014-0078-0 |
|
received in 2014-08-07, accepted in 2014-12-16, 发布年份 2015 | |
![]() |
【 摘 要 】
Endorectal ultrasonography (ERUS) and magnetic resonance imaging (MRI) allow exploring the morphology of the rectum in detail. Use of such data, especially assessment of the rectal wall, is an important tool for ascertaining the perianal fistula localization as well as stage of the cancer and planning it appropriate treatment, as stage T3 tumors are usually treated with neoadjuvant therapy, whereas T2 tumors are initially managed surgically. The only advantage of ERUS over MRI is the possibility of assessing T1 tumors that could be treated by transanal endoscopic microsurgery. However, MRI is better for visualizing most radiological prognostic features in rectal or anal cancer such as a circumferential resection margin less than 1 mm, T stage at T1-T2 or T3 tumors with extramural extension less than 5 mm, absence of extramural vascular invasion, N stage at N0/N1, and tumors located in the middle or upper third of the rectum. It can also evaluate the intersphincteric space or levator ani muscle involvement. Increased signal on diffusion weighted imaging (DWI) and low apparent diffusion coefficient (ADC) values as well as an irregular contour and heterogeneous internal signal intensity seem to predict the involvement of pelvic lymphatic nodes better than their size alone. Computed tomography as well as other examination techniques, including digital rectal examination, contrast edema, recto- and colonoscopy, are less useful in staging of rectal cancer but still are very important screening tools.
【 授权许可】
2015 Burdan et al.; licensee BioMed Central.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20150201030243611.pdf | 1843KB | ![]() |
|
Figure 5. | 50KB | Image | ![]() |
Figure 4. | 88KB | Image | ![]() |
Figure 3. | 93KB | Image | ![]() |
Figure 2. | 76KB | Image | ![]() |
Figure 1. | 40KB | Image | ![]() |
【 图 表 】
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
【 参考文献 】
- [1]Clinical orientated anatomy. 5th edition. Lippincott Williams & Wilkins, Baltimore; 2006.
- [2]Iafrate F, Laghi A, Paolantonio P, Rengo M, Mercantini P, Ferri M, et al.: Preoperative staging of rectal cancer with MRI imaging: correlation with surgical and histopathologic findings. Radiographics 2006, 26:701-14.
- [3]Diop M, Parratte B, Tatu L, Vuillier F, Brunelle S, Monnier G: “Mesorectum”: the surgical value of an anatomical approach. Surg Radiol Anat 2003, 25:290-304.
- [4]Allen SD, Gada V, Blunt DM: Variation of mesorectal volume with abdominal fat volume in patients with rectal carcinoma: assessment with MRI. Br J Radiol 2007, 80:242-7.
- [5]Torkzad MR, Hansson KA, Lindholm J, Martling A, Blomqvist L: Significance of mesorectal volume in staging of rectal cancer with magnetic resonance imaging and the assessment of involvement of the mesorectal fascia. Eur Radiol 2007, 17:1694-9.
- [6]Tudyka V, Blomqvist L, Beets-Tan RG, Boelens PG, Valentini V, van de Velde CJ, et al.: EURECCA consensus conference highlights about colon & rectal cancer multidisciplinary management: the radiology experts review. Eur J Surg Oncol 2014, 40:469-75.
- [7]Sudol-Szopinska I: Endosonographic examination of the anal canal and rectum. In Principles for ultrasound examination. Edited by Jakubowski W. Roztoczanska Szkoła Ultrasonografii, Zamosc; 2011:140-4.
- [8]Sudol-Szopinska I, Kolodziejczak M, Szopinski TR: The accuracy of a postprocessing technique − volume render mode − in three-dimensional endoanal ultrasonography of anal abscesses and fistulas. Dis Colon Rectum 2011, 54:238-44.
- [9]Kolodziejczak M, Santoro GA, Slapa RZ, Szopinski T, Sudol-Szopinska I: Usefulness of 3D transperineal ultrasound in severe stenosis of the anal canal: preliminary experience in four cases. Tech Coloproctol 2014, 18:495-501.
- [10]Kolodziejczak M, Sudol-Szopinska I, Wilczynska A, Bierca J: Utility of transperineal and anal ultrasonography in the diagnostics of hidradenitis suppurativa and its differentiation from a rectal fistula. Postepy Hig Med Dosw (Online) 2012, 66:838-42.
- [11]Sudol-Szopinska I, Kucharczyk A: Upper rectal fistulas: endoanal ultrasonography vs MR. J Ultrason 2014, 14:142-51.
- [12]Fox A, Tietze PH, Ramakrishnan K: Anorectal conditions: anal fissure and anorectal fistula. FP Essent 2014, 419:20-7.
- [13]Fox A, Tietze PH, Ramakrishnan K: Anorectal conditions: fecal incontinence. FP Essent 2014, 419:35-47.
- [14]Kolev NY, Tonev AY, Ignatov VL, Zlatarov AK, Bojkov VM, Kirilova TD, et al.: The role of 3-D endorectal ultrasound in rectal cancer: our experience. Int Surg 2014, 99:106-11.
- [15]Edelman BR, Weiser MR: Endorectal ultrasound: its role in the diagnosis and treatment of rectal cancer. Clin Colon Rectal Surg 2008, 21:167-77.
- [16]Hildebrandt U, Feifel G: Endosonographic possibilities in the lower alimentary tract. Baillieres Clin Gastroenterol 1994, 8:635-50.
- [17]Beynon J: Endorectal sonography − the position now. Surg Oncol 1992, 1:189-91.
- [18]Hoeffel C, Mulé S, Laurent V, Bouché O, Volet J, Soyer P: Primary rectal cancer local staging. Diagn Interv Imaging 2014, 95:485-94.
- [19]Carrington EV, Grossi U, Knowles CH, Scott SM: Normal values for high-resolution anorectal manometry: a time for consensus and collaboration. Neurogastroenterol Motil 2014, 26:1356-7.
- [20]Hong YK, Choi YJ, Kang JG: Correlation of histopathology with anorectal manometry following stapled hemorrhoidopexy. Ann Coloproctol 2013, 29:198-204.
- [21]Visscher AP, Lam TJ, Hart N, Felt-Bersma RJ: Fecal incontinence, sexual complaints, and anorectal function after third-degree obstetric anal sphincter injury (OASI): 5-year follow-up. Int Urogynecol J 2014, 25:607-13.
- [22]Carrington EV, Brokjaer A, Craven H, Zarate N, Horrocks EJ, Palit S, et al.: Traditional measures of normal anal sphincter function using high-resolution anorectal manometry (HRAM) in 115 healthy volunteers. Neurogastroenterol Motil 2014, 26:625-35.
- [23]Nowakowski M, Tomaszewski KA, Herman RM, Salowka J, Romaniszyn M, Rubinkiewicz M, et al.: Developing a new electromyography-based algorithm to diagnose the etiology of fecal incontinence. Int J Colorectal Dis 2014, 29:747-54.
- [24]Brown G, Daniels IR, Richardson C, Revell P, Peppercorn D, Bourne M: Techniques and trouble-shooting in high spatial resolution thin slice MRI for rectal cancer. Br J Radiol 2005, 78:245-51.
- [25]Muthusamy VR, Chang KJ: Optimal methods for staging rectal cancer. Clin Cancer Res 2007, 13(22 Pt 2):6877s-84.
- [26]Kim SH, Lee JM, Lee MW, Kim GH, Han JK, Choi BI: Diagnostic accuracy of 3.0-Tesla rectal magnetic resonance imaging in preoperative local staging of primary rectal cancer. Invest Radiol 2008, 43:587-93.
- [27]Akin O, Nessar G, Agildere AM, Aydog G: Preoperative local staging of rectal cancer with endorectal MRI imaging: comparison with histopathologic findings. Clin Imaging 2004, 28:432-8.
- [28]Dinter DJ, Hofheinz RD, Hartel M, Kaehler GF, Neff W, Diehl S: Preoperative staging of rectal tumors: comparison of endorectal ultrasound, hydro-CT, and high-resolution endorectal MRI. Onkologie 2008, 31:230-5.
- [29]Stikova E: Magnetic resonance imaging safety: principles and guidelines. Prilozi 2012, 33:441-72.
- [30]Mocarska A, Starosławska E, Zelazowska-Cieslinska I, Kubiatowski T, Kolak A, Cisek P, et al.: Principles for magnetic resonance examination in case of the cervical cancer. Curr Issues Pharm Med Sci 2013, 26:414-7.
- [31]Lalwani N, Moshiri M, Lee JH, Bhargava P, Dighe MK: Magnetic resonance imaging of pelvic floor dysfunction. Radiol Clin North Am 2013, 51:1127-39.
- [32]Torkzad MR, Påhlman L, Glimelius B: Magnetic resonance imaging (MRI) in rectal cancer: a comprehensive review. Insights Imaging 2010, 1:245-67.
- [33]Taylor FG, Swift RI, Blomqvist L, Brown G: A systematic approach to the interpretation of preoperative staging MRI for rectal cancer. AJR Am J Roentgenol 2008, 191:1827-35.
- [34]Zhang XM, Zhang HL, Yu D, Dai Y, Bi D, Prince MR, et al.: 3-T MRI of rectal carcinoma: preoperative diagnosis, staging, and planning of sphincter-sparing surgery. AJR Am J Roentgenol 2008, 190:1271-8.
- [35]MERCURY Study Group: Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. BMJ. 2006;333:779.
- [36]Piippo U, Pääkkö E, Mäkinen M, Mäkelä J: Local staging of rectal cancer using the black lumen magnetic resonance imaging technique. Scand J Surg 2008, 97:237-42.
- [37]Oberholzer K, Menig M, Pohlmann A, Junginger T, Heintz A, Kreft A, et al.: Rectal cancer: assessment of response to neoadjuvant chemoradiation by dynamic contrast-enhanced MRI. J Magn Reson Imaging 2013, 38:119-26.
- [38]Attenberger UI, Pilz LR, Morelli JN, Hausmann D, Doyon F, Hofheinz R, et al. Multi-parametric MRI of rectal cancer − do quantitative functional MRI measurements correlate with radiologic and pathologic tumor stages? Eur J Radiol, in press.
- [39]Stollfuss JC, Becker K, Sendler A, Seidl S, Settles M, Auer F, et al.: Rectal carcinoma: high-spatial-resolution MRI imaging and T2 quantification in rectal cancer specimens. Radiology 2006, 241:132-41.
- [40]Hussain SM, Outwater EK, Siegelman ES: Mucinous versus nonmucinous rectal carcinomas: differentiation with MRI imaging. Radiology 1999, 213:79-85.
- [41]Kim MJ, Park JS, Park SI, Kim NK, Kim JH, Moon HJ, et al.: Accuracy in differentiation of mucinous and nonmucinous rectal carcinoma on MRI imaging. J Comput Assist Tomogr 2003, 27:48-55.
- [42]Hamilton SR, Lauri AA: IARC (The International Agency for Research on Cancer). WHO Classification of Tumours of the Digestive System (IARC WHO Classification of Tumours). 4th edition. World Health Organization, Lyon; 2010.
- [43]Sauer R, Becker H, Hohenberger W, Rödel C, Wittekind C, Fietkau R, et al.: Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004, 351:1731-40.
- [44]Nagtegaal ID, van de Velde CJ, Marijnen CA, van Krieken JH, Quirke P: Low rectal cancer: a call for a change of approach in abdominoperineal resection. J Clin Oncol 2005, 23:9257-64.
- [45]Zorcolo L, Fantola G, Cabras F, Marongiu L, D’Alia G, Casula G: Preoperative staging of patients with rectal tumors suitable for transanal endoscopic microsurgery (TEM): comparison of endorectal ultrasound and histopathologic findings. Surg Endosc 2009, 23:1384-9.
- [46]Wieder HA, Rosenberg R, Lordick F, Geinitz H, Beer A, Becker K, et al.: Rectal cancer: MRI imaging before neoadjuvant chemotherapy and radiation therapy for prediction of tumor-free circumferential resection margins and long-term survival. Radiology 2007, 243:744-51.
- [47]Laghi A, Ferri M, Catalano C, Baeli I, Iannaccone R, Iafrate F, et al.: Local staging of rectal cancer with MRI using a phased array body coil. Abdom Imaging 2002, 27:425-31.
- [48]Vliegen R, Dresen R, Beets G, Daniels-Gooszen A, Kessels A, van Engelshoven J, et al.: The accuracy of multi-detector row CT for the assessment of tumor invasion of the mesorectal fascia in primary rectal cancer. Abdom Imaging 2008, 33:604-10.
- [49]Maizlin ZV, Brown JA, So G, Brown C, Phang TP, Walker ML, et al.: Can CT replace MRI in preoperative assessment of the circumferential resection margin in rectal cancer? Dis Colon Rectum 2010, 53:308-14.
- [50]Pedersen BG, Moran B, Brown G, Blomqvist L, Fenger-Gron M, Laurberg S: Reproducibility of depth of extramural tumor spread and distance to circumferential resection margin at rectal MRI: enhancement of clinical guidelines for neoadjuvant therapy. AJR Am J Roentgenol 2011, 197:1360-6.
- [51]Smith N, Brown G: Preoperative staging of rectal cancer. Acta Oncol 2008, 47:20-31.
- [52]Beets-Tan RG, Beets GL, Vliegen RF, Kessels AG, Van Boven H, De Bruine A, et al.: Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery. Lancet 2001, 357:497-504.
- [53]Brown G, Radcliffe AG, Newcombe RG, Dallimore NS, Bourne MW, Williams GT: Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging. Br J Surg 2003, 90:355e64.
- [54]Bokey EL, Chapuis PH, Dent OF, Newland RC, Koorey SG, Zelas PJ, et al.: Factors affecting survival after excision of the rectum for cancer: a multivariate analysis. Dis Colon Rectum 1997, 40:3e10.
- [55]Hunter CJ, Garant A, Vuong T, Artho G, Lisbona R, Tekkis P, et al.: Adverse features on rectal MRI identify a high-risk group that may benefit from more intensive preoperative staging and treatment. Ann Surg Oncol 2012, 19:1199e205.
- [56]Messenger DE, Driman DK, Kirsch R: Developments in the assessment of venous invasion in colorectal cancer: implications for future practice and patient outcome. Hum Pathol 2012, 43:965-73.
- [57]Dighe S, Swift I, Magill L, Handley K, Gray R, Quirke P, et al.: Accuracy of radiological staging in identifying high-risk colon cancer patients suitable for neoadjuvant chemotherapy: a multicentre experience. Colorectal Dis 2012, 14:438-44.
- [58]Bugg WG, Andreou AK, Biswas D, Toms AP, Williams SM: The prognostic significance of MRI-detected extramural venous invasion in rectal carcinoma. Clin Radiol 2014, 69:619-23.
- [59]Smith NJ, Barbachano Y, Norman AR, Swift RI, Abulafi AM, Brown G: Prognostic significance of magnetic resonance imaging-detected extramural vascular invasion in rectal cancer. Br J Surg 2008, 95:229-36.
- [60]Scharitzer M, Ba-Ssalamah A, Ringl H, Kölblinger C, Grünberger T, Weber M, et al.: Preoperative evaluation of colorectal liver metastases: comparison between gadoxetic acidenhanced 3.0 T MRI and contrast enhanced MDCT with histopathological correlation. Eur Radiol 2013, 23:2187e96.
- [61]Le Bihan D, Poupon C, Amadon A, Lethimonnier F: Artifacts and pitfalls in diffusion MRI. J Magn Reson Imaging 2006, 24:478-88.
- [62]Siegelman ES, Chauhan A: MR characterization of focal liver lesions: pearls and pitfalls. Magn Reson Imaging Clin N Am 2014, 22:295-313.
- [63]Lambregts DM, Cappendijk VC, Maas M, Beets GL, Beets-Tan RG: Value of MRI and diffusion-weighted MRI for the diagnosis of locally recurrent rectal cancer. Eur Radiol 2011, 21:1250-8.
- [64]Furman AM, Dit Yafawi JZ, Soubani AO: An update on the evaluation and management of small pulmonary nodules. Future Oncol 2013, 9:855-65.
- [65]Kim JH, Beets GL, Kim MJ, Kessels AG, Beets-Tan RG: High-resolution MRI imaging for nodal staging in rectal cancer: are there any criteria in addition to the size? Eur J Radiol 2004, 52:78-83.
- [66]Hadfield MB, Nicholson AA, MacDonald AW, Farouk R, Lee PW, Duthie GS, et al.: Preoperative staging of rectal carcinoma by magnetic resonance imaging with a pelvic phased array coil. Br J Surg 1997, 84:529-31.
- [67]Brown G, Kirkham A, Williams GT, Bourne M, Radcliffe AG, Sayman J, et al.: High-resolution MRI of the anatomy important in total mesorectal excision of the rectum. AJR Am J Roentgenol 2004, 182:431-9.
- [68]Brown G, Richards CJ, Bourne MW, Newcombe RG, Radcliffe AG, Dallimore NS, et al.: Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MRI imaging with histopathologic comparison. Radiology 2003, 227:371-7.
- [69]Hermanek P, Merkel S, Fietkau R, Rodel C, Hohenberger W: Regional lymph node metastasis and locoregional recurrence of rectal carcinoma in the era of TME [corrected] surgery. Implications for treatment decisions. Int J Colorectal Dis 2010, 5:359-68.
- [70]Taylor FG, Quirke P, Heald RJ, Moran B, Blomqvist L, Swift I, et al.: Preoperative high-resolution magnetic resonance imaging can identify good prognosis stage I, II, and III rectal cancer best managed by surgery alone: a prospective, multicenter, European study. Ann Surg 2011, 253:711-9.
- [71]Taylor FG, Quirke P, Heald RJ, Moran B, Blomqvist L, Swift I, et al.: One millimetre is the safe cut-off for magnetic resonance imaging prediction of surgical margin status in rectal cancer. Br J Surg 2011, 98:872-9.
- [72]Mizukami Y, Ueda S, Mizumoto A, Sasada T, Okumura R, Kohno S, et al.: Diffusion-weighted magnetic resonance imaging for detecting lymph node metastasis of rectal cancer. World J Surg 2011, 35:895-9.
- [73]Koh DM, Brown G, Temple L, Raja A, Toomey P, Bett N, et al.: Rectal cancer: mesorectal lymph nodes at MRI imaging with USPIO versus histopathologic findings-initial observations. Radiology 2004, 231:91-9.
- [74]Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, et al.: Ferumoxtran-10-enhanced MRI lymphangiography: does contrast-enhanced imaging alone suffice for accurate lymph node characterization? AJR 2006, 186:144-8.
- [75]Lambregts DM, Heijnen LA, Maas M, Rutten IJ, Martens MH, Backes WH, et al.: Gadofosveset-enhanced MRI for the assessment of rectal cancer lymph nodes: predictive criteria. Abdom Imaging 2013, 38:720-7.
- [76]Bipat S, Glas AS, Slors FJ, Zwinderman AH, Bossuyt PM, Stoker J: Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MRI imaging–a meta-analysis. Radiology 2004, 232:7737-83.
- [77]Puli SR, Reddy JB, Bechtold ML, Choudhary A, Antillon MR, Brugge WR: Accuracy of endoscopic ultrasound to diagnose nodal invasion by rectal cancers: a meta-analysis and systematic review. Ann Surg Oncol 2009, 16:1255-65.