Effects of 92% oxygen administration on cognitive performance and physiological changes of intellectually and developmentally disabled people

Journal of Physiological Anthropology

Soon-Cheol Chung⁴  Dae-Woon Lim¹  Young Chil Choi⁵  Hyun-Jun Kim³  Sung-Phil Kim²  Ul-Ho Jeong⁴  Jung-Chul Lee⁴  Sung-Jun Park⁴  Ji-Hye Baek⁴  Mi-Hyun Choi⁴  Hyung-Sik Kim⁴ 

[1] Department of Information & Communication Engineering, Dongguk University, 30 Pildong-ro, Seoul 100-715, South Korea;Department of Design Human Engineering, Ulsan National Institute of Science and Technology, 50 UNIST-gil, Ulsan 689-798, South Korea;Department of Obstetrics & Gynecology, Konkuk University, 268 Chungwon-daero, Chungju Chungbuk-do 380-701, South Korea;Department of Biomedical Engineering, BK21+ Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, 268 Chungwon-daero, Chungju Chungbuk-do 380-701, South Korea;Department of Radiology, School of Medicine, Konkuk University, 268 Chungwon-daero, Chungju Chungbuk-do 380-701, South Korea

关键词: Intellectual and developmental disability;    Heart rate;    Blood oxygen saturation;    Cognitive performance;    Oxygen administration;   

Others  :  1132913
DOI  :  10.1186/s40101-015-0043-9

 received in 2014-10-03, accepted in 2015-01-19,  发布年份 2015

【 摘 要 】

Background

The present study addressed how 92% oxygen administration affects cognitive performance, blood oxygen saturation (SpO₂), and heart rate (HR) of intellectually and developmentally disabled people.

Methods

Seven males (28.9 ± 1.8 years) and seven females (34.4 ± 8.3 years) with intellectual and developmental disabilities (disabled level 2.1 ± 0.5) completed an experiment consisting a 0-back task with normal air (21% oxygen) administered in one run and hyperoxic air (92% oxygen) administered in the other run. The experimental sequence in each run consisted of a 1-min adaptation phase, 2-min control phase, and 2-min 0-back task phase, where SpO₂ and HR were gauged for each phase.

Results

The administration of 92% oxygen increased 0-back task performance of intellectually and developmentally disabled people, in association with increased SpO₂ and decreased HR. Our results demonstrate that sufficient oxygen supply subserving cognitive functions, even as a short-term effect, could increase cognitive ability for the intellectually and developmentally disabled people.

Conclusions

It is concluded that enriched oxygen can positively affect, at least in the short-term, the working memory of those with intellectual and developmental disability.

【 授权许可】

   
2015 Kim et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

Figure 2.

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