Quality of life among tuberculosis (TB), TB retreatment and/or TB-HIV co-infected primary public health care patients in three districts in South Africa

Health and Quality of Life Outcomes

Bomkazi Tutshana¹  Gugu Mchunu¹  Gladys Matseke¹  Pamela Naidoo³  Karl Peltzer²  Julia Louw¹ 

[1] HIV/STI and TB (HAST) Research Programme, Human Sciences Research Council, Pretoria, Durban and Cape Town, South Africa;Department of Psychology, University of the Free State, Bloemfontein, South Africa;Department of Psychology, University of the Western Cape, Cape Town, South Africa

关键词: South Africa;    Quality of life;    HIV and AIDS;    Tuberculosis patients;    Social functioning;   

Others  :  825446
DOI  :  10.1186/1477-7525-10-77

 received in 2012-04-21, accepted in 2012-06-28,  发布年份 2012

【 摘 要 】

Introduction

TB and HIV co-morbidity amount to a massive burden on healthcare systems in many countries. This study investigates health related quality of life among tuberculosis (TB), TB retreatment and TB-HIV co-infected public primary health care patients in three districts in South Africa.

Methods

A cross sectional study was conducted among 4900 TB patients who were in the first month of anti-TB treatment in primary public health care clinics in three districts in South Africa. Quality of life was assessed using the social functioning (SF)-12 Health Survey through face to face interviews. Associations of physical health (Physical health Component Summary = PCS) and mental health (Mental health Component Summary = MCS) were identified using logistic regression analyses.

Results

The overall physical and mental health scores were 42.5 and 40.7, respectively. Emotional role, general health and bodily pain had the lowest sub-scale scores, while energy and fatigue and mental health had the highest domain scores. Independent Kruskal–Wallis tests found significant positive effects of being TB-HIV co-infected on the domains of mental health functioning, emotional role, energy and fatigue, social function and physical role, while significant negative effects were observed on general health, bodily pain and physical function. In multivariable analysis higher educational, lower psychological distress, having fewer chronic conditions and being HIV negative were significantly positively associated with PCS, and low poverty, low psychological distress and being HIV positive were positively significantly associated with MCS.

Conclusion

TB and HIV weaken patients’ physical functioning and impair their quality of life. It is imperative that TB control programmes at public health clinics design strategies to improve the quality of health of TB and HIV co-infected patients.

【 授权许可】

   
2012 Louw et al.; Licensee BioMed Central Ltd.

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