Prevalence of the metabolic syndrome using two proposed definitions in a Japanese-Brazilians community

Diabetology & Metabolic Syndrome

Milton C Foss⁴  Laercio J Franco³  Luciana Z Monteiro⁴  Amaury L Dal Fabbro³  Ana E Pace²  Roberta C Figueiredo³  Regina CG Andrade¹  Patricia M Gomes⁴  Maria C Foss-Freitas⁴ 

[1] Ribeirão Preto Medical School, Ribeirão Preto Pharmacy School, Sao Paulo University-Brazil, Sao Paulo, Brazil;Ribeirão Preto Nurse School, Sao Paulo University-Brazil, Sao Paulo, Brazil;Department of Social Medicine, Sao Paulo University-Brazil, Sao Paulo, Brazil;Department of Internal Medicine, Sao Paulo University-Brazil, Sao Paulo, Brazil

关键词: Waist circumference;    NCEP;    IDF;    Japanese-Brazilians;    Metabolic syndrome;   

Others  :  814886
DOI  :  10.1186/1758-5996-4-38

 received in 2012-06-12, accepted in 2012-08-08,  发布年份 2012

【 摘 要 】

Metabolic Syndrome (MetS) is associated with increased risk of morbi-mortality, thus the characterization of the population magnitude of this syndrome is critical for allocating health care. However, prevalence estimates of MetS in the same population could differ depending on the definition used. Therefore, we compared the prevalence of the MetS using definitions proposed by: National Cholesterol Education Panel Revised (NCEP) and International Diabetes Federation (IDF) 2009 in a Japanese-Brazilians community (131 individuals, age 57 ± 16 years, 1st and 2nd generation). All individuals went through a clinical and laboratorial evaluation for assessment of weigh, height, waist circumference, blood pressure, triglycerides, HDL-cholesterol and fasting plasma glucose. The prevalence of MetS was 26.7% (n = 35) and 37.4% (n = 49) under the NCEP and IDF definitions, respectively. Despite higher blood pressure measurements, waist circumference and serum triglyceride levels and lower HDL cholesterol levels (p < 0.01), individuals identified with MetS did not show increased blood glucose levels. IDF definition classified 14 individuals (10.7%) with MetS that were not classified under the NCEP and 35 individuals were identified with MetS by both criteria. We observed, in this group, more severe lipid disorders, compared to individuals identified only under the IDF definition, and the BMI and waist circumference (p = 0.01; p = 0.006, respectively) were lower. In conclusion, the IDF revised criteria, probably because of the ethnic specific values of waist circumference, was able to identify a larger number of individuals with MetS. However, our data suggesting that additional studies are necessary to define best MetS diagnostic criteria in this population.

【 授权许可】

   
2012 Foss-Freitas et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Reaven GM: Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988, 37(12):1595-1607.
• [2]Eckel RH, Grundy SM, Zimmet PZ: The metabolic syndrome. Lancet 2005, 365(9468):1415-1428.
• [3]Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, et al.: The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002, 288(21):2709-2716.
• [4]Wilson PW, D'Agostino RB, Parise H, Sullivan L, Meigs JB: Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005, 112(20):3066-3072.
• [5]Ford ES: The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study. Atherosclerosis 2004, 173(2):309-314.
• [6]Alberti KG, Zimmet PZ: Should we dump the metabolic syndrome? No. BMJ 2008, 336(7645):641.
• [7]Alberti KG, Zimmet P, Shaw J: The metabolic syndrome--a new worldwide definition. Lancet 2005, 366(9491):1059-1062.
• [8]Leslie BR: Metabolic syndrome: historical perspectives. Am J Med Sci 2005, 330(6):264-268.
• [9]Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) JAMA 2001, 285(19):2486-2497.
• [10]Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al.: Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112(17):2735-2752.
• [11]Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al.: Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009, 120(16):1640-1645.
• [12]Arai H, Yamamoto A, Matsuzawa Y, Saito Y, Yamada N, Oikawa S, et al.: Prevalence of metabolic syndrome in the general Japanese population in 2000. J Atheroscler Thromb 2006, 13(4):202-208.
• [13]V Diretrizes Brasileiras de Hipertensão Arterial Arq Bras Cardiol 2007, 89(3):e27-e79.
• [14]Laaksonen DE, Lakka HM, Niskanen LK, Kaplan GA, Salonen JT, Lakka TA: Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am J Epidemiol 2002, 156(11):1070-1077.
• [15]Yoneda M, Yamane K, Jitsuiki K, Nakanishi S, Kamei N, Watanabe H, et al.: Prevalence of metabolic syndrome compared between native Japanese and Japanese-Americans. Diabetes Res Clin Pract 2008, 79(3):518-522.
• [16]Katzmarzyk PT, Janssen I, Ross R, Church TS, Blair SN: The importance of waist circumference in the definition of metabolic syndrome: prospective analyses of mortality in men. Diabetes Care 2006, 29(2):404-409.
• [17]Ford ES, Giles WH: A comparison of the prevalence of the metabolic syndrome using two proposed definitions. Diabetes Care 2003, 26(3):575-581.
• [18]Prasad SB, Fahrtash F, Malaiapan Y, Meredith IT, Cameron J: Prevalence, detection, and management of the metabolic syndrome in patients with acute myocardial infarction: role of an obesity-centric definition. Cardiol Res Pract 2010, 2010:7. 10.4061/2010/814561. ID814561
• [19]Kassi E, Pervanidou P, Kaltsas G, Chrousos G: Metabolic syndrome: definitions and controversies. BMC Med 2011, 9:48. BioMed Central Full Text
• [20]Xavier NP, Chaim RC, Gimeno SG, Ferreira SR, Hirai AT, Padovani CR, et al.: Prevalence of metabolic syndrome in Japanese-Brazilians according to specific definitions for ethnicity. Metab Syndr Relat Disord 2010, 8(2):143-148.
• [21]Gupta A, Gupta V: Metabolic syndrome: what are the risks for humans? Biosci Trends 2010, 4(5):204-212.
• [22]Rosenbaum P, Gimeno SG, Sanudo A, Franco LJ, Ferreira SR: Analysis of criteria for metabolic syndrome in a population-based study of Japanese-Brazilians. Diabetes Obes Metab 2005, 7(4):352-359.