Posttraumatic stress symptoms after solid-organ transplantation: preoperative risk factors and the impact on health-related quality of life and life satisfaction

Health and Quality of Life Outcomes

Hans-Bernd Rothenhäusler¹  Till Krauseneck¹  Andreas Baranyi² 

[1] Department of Psychiatry, Ludwig-Maximilians University of Munich, Nußbaumstraße 7, Munich 80336, Germany;Department of Psychiatry, University of Medicine of Graz, Auenbruggerplatz 31, Graz 8036, Austria

关键词: Life satisfaction;    Health-related quality of life;    Preoperative risk factors;    Posttraumatic stress symptoms;    Intensive care unit;    Solid-organ transplantation;   

Others  :  823501
DOI  :  10.1186/1477-7525-11-111

 received in 2013-03-12, accepted in 2013-07-01,  发布年份 2013

【 摘 要 】

Background

Solid-organ transplantations (SOT) are usually life-saving high-tech medical procedures. The transplantation itself and the intensive care unit stay could be traumatic stressors triggering posttraumatic stress symptoms (PTSS). Our retrospective follow-up study aimed to explore preoperative risk factors of PTSS in a cohort of SOT recipients, and we investigated how PTSS are associated with health-related quality of life (HRQOL) and life satisfaction.

Methods

126 SOT recipients were enrolled in this investigation. Psychiatric examination of all SOT candidates based on the Transplant Evaluation Rating Scale was carried out before SOT, and after SOT, recipients completed the PTSS-10, the SF-36 and the FLZ.

Results

After the surgical intervention 19 (15.1%) SOT recipients had clinical significant PTSS. Preoperative risk factors for developing postoperative PTSS were: 1.) preexisting psychiatric morbidity, 2.) history of retransplantation, 3.) chronic benzodiazepine consumption, 4.) age, and 5.) type of transplantation.

SOT-related PTSS were associated with maximal decrements in HRQOL and life satisfaction. The following HRQOL and life satisfaction domains were affected: Physical Functioning, Role Physical, Pain, General Health, Vitality, Social Functioning, Role Emotional, Mental Health, Occupation/Work and Character/Own Skills.

Conclusion

SOT recipients may face a major risk of transplantation- and treatment-related PTSS and the development of impairments to HRQOL and life satisfaction.

【 授权许可】

   
2013 Baranyi et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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