Retroperitoneal composite pheochromocytoma-ganglioneuroma : a case report and review of literature

Diagnostic Pathology

Guohua Yu²  Weidong Yao²  Houcai Liu²  Guimei Qu²  Zhiqiang Lang²  Lei Jiang²  Li Cai²  Jitao Wu²  Jinchen Hu¹ 

[1] Department of Abdominal Surgery, Affiliated Yantai Yuhuangding Hospital, Medical College of Qingdao University, Yantai, China;Department of Pathology, Affiliated Yantai Yuhuangding Hospital, Medical College of Qingdao University, No.20, Yuhuangding East Road, Yantai 264000, China

关键词: Ganglioneuroma;    Retroperitoneal;    Composite pheochromocytoma/paraganglioma;   

Others  :  807191
DOI  :  10.1186/1746-1596-8-63

 received in 2013-02-01, accepted in 2013-04-10,  发布年份 2013

【 摘 要 】

Composite pheochromocytoma/paraganglioma is a rare tumor with elements of pheochromocytoma/paraganglioma and neurogenic tumor. Most were located in the adrenal glands, and extra-adrenal composite pheochromocytoma is extremely rare. Only 4 cases in the retroperitoneum have been described in the online database PUBMED. Here, we report a case of retroperitoneal extra-adrenal composite pheochromocytoma and review the related literature.

【 授权许可】

   
2013 Hu et al.; licensee BioMed Central Ltd.

【 图 表 】

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【 参考文献 】

• [1]Disick GI, Palese MA: Extra-adrenal pheochromocytoma: diagnosis and management. Curr Urol Rep 2007, 8:83-88.
• [2]Chen CH, Boag AH, Beiko DT, Siemens DR, Froese A, Isotalo PA: Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection. Can Urol Assoc J 2009, 3:E45-E48.
• [3]Gong J, Wang X, Chen X, Chen N, Huang R, Lu C, Chen D, Zeng H, Zhou Q: Adrenal and extra-adrenal nonfunctioning composite pheochromocytoma/paraganglioma with immunohistochemical ectopic hormone expression: comparison of two cases. Urol Int 2010, 85:368-372.
• [4]Hirasaki S, Kanzaki H, Okuda M, Suzuki S, Fukuhara T, Hanaoka T: Composite paraganglioma-ganglioneuroma in the retroperitoneum. World J Surg Oncol 2009, 7:81. BioMed Central Full Text
• [5]Pytel P, Krausz T, Wollmann R, Utset MF: Ganglioneuromatous paraganglioma of the cauda equina–a pathological case study. Hum Pathol 2005, 36:444-446.
• [6]Tohme CA, Mattar WE, Ghorra CS: Extra-adrenal composite pheochromocytoma-ganglioneuroma. Saudi Med J 2006, 27:1594-1597.
• [7]Yoshimi N, Tanaka T, Hara A, Bunai Y, Kato K, Mori H: Extra-adrenal pheochromocytoma-ganglioneuroma. A case report. Pathol Res Pract 1992, 188:1098-1100. discussion 1101–1103
• [8]Linnoila RI, Keiser HR, Steinberg SM, Lack EE: Histopathology of benign versus malignant sympathoadrenal paragangliomas: clinicopathologic study of 120 cases including unusual histologic features. Hum Pathol 1990, 21:1168-1180.
• [9]Khan AN, Solomon SS, Childress RD: Composite pheochromocytoma-ganglioneuroma: a rare experiment of nature. Endocr Pract 2010, 16:291-299.
• [10]Shahani S, Nudelman RJ, Nalini R, Kim HS, Samson SL: Ectopic corticotropin-releasing hormone (CRH) syndrome from metastatic small cell carcinoma: a case report and review of the literature. Diagn Pathol 2010, 5:56. BioMed Central Full Text
• [11]Mahajan H, Lee D, Sharma R, Chin P, Watt WH, McBride G, Bilous M: Composite phaeochromocytoma-ganglioneuroma, an uncommon entity: report of two cases. Pathology 2010, 42:295-298.
• [12]Kimura N, Watanabe T, Fukase M, Wakita A, Noshiro T, Kimura I: Neurofibromin and NF1 gene analysis in composite pheochromocytoma and tumors associated with von Recklinghausen’s disease. Mod Pathol 2002, 15:183-188.
• [13]Gullu S, Gursoy A, Erdogan MF, Dizbaysak S, Erdogan G, Kamel N: Multiple endocrine neoplasia type 2A/localized cutaneous lichen amyloidosis associated with malignant pheochromocytoma and ganglioneuroma. J Endocrinol Invest 2005, 28:734-737.
• [14]Tischler AS: Divergent differentiation in neuroendocrine tumors of the adrenal gland. Semin Diagn Pathol 2000, 17:120-126.
• [15]Sun YH, Wen W, Wu JH, Song JM, Guan H, Wang KX, Xu MQ: Endolymphatic sac tumor: case report and review of the literature. Diagn Pathol 2012, 7:36. BioMed Central Full Text
• [16]Lam KY, Lo CY: Composite pheochromocytoma-ganglioneuroma of the adrenal gland: an uncommon entity with distinctive clinicopathologic features. Endocr Pathol 1999, 10:343-352.
• [17]Comstock JM, Willmore-Payne C, Holden JA, Coffin CM: Composite pheochromocytoma: a clinicopathologic and molecular comparison with ordinary pheochromocytoma and neuroblastoma. Am J Clin Pathol 2009, 132:69-73.