期刊论文详细信息
Clinical and Molecular Allergy
The perception of allergen-specific immunotherapy among pediatricians in the primary care setting
Giorgio Walter Canonica3  Giovanni Passalacqua3  Carlo Lombardi2  Ermanno Praitano4  Paolo Meglio5  Massimo Landi1 
[1] Italian Federation of Pediatric Primary Care, Turin, Italy;Allergy Unit, Department of Internal Medicine, Sant’Orsola-Poliambulanza Hospital, Brescia, Italy;Allergy and Respiratory Diseases, DIMI, IRCCS San Martino Hospital-IST-University of Genoa, Pad.Maragliano, L.go R Benzi 10, Genoa, 16133, Italy;Italian Federation of Pediatric Primary Care, Bari, Italy;Italian Federation of Pediatric Primary Care, Rome, Italy
关键词: Allergen immunotherapy;    Allergic respiratory disease;    Children;    Primary care pediatrician;   
Others  :  1221673
DOI  :  10.1186/s12948-015-0021-0
 received in 2015-03-17, accepted in 2015-05-18,  发布年份 2015
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【 摘 要 】

Background

Allergic respiratory diseases are constantly increasing in prevalence. Allergen Immunotherapy (AIT) represent a valuable therapeutic tool as symptomatic and preventative approach, expecially in children. In Italy, primary care pediatricians (PCP) represent the first-line contact and interface for prescription, use and management of AIT. We attempted to evaluate the perception of AIT practice among PCP.

Methods

A questionnaire was built-up, based on literature, guidelines and with the contribution of pediatricians. The questionnaire, including 12 items, was e-mailed to 180 PCP, randomly chosen from mailing lists. The questionnaire explored the personal perception of AIT, the comparison between subcutaneous and sublingual AIT and the overall awareness about the treatment.

Results

130 questionnaires were eligible for analysis. There was a satisfactory knowledge of the characteristics of AIT, its aims and limits, although the positioning of the treatment in guidelines was insufficiently known. Overall, the prescription of AIT made by other specialists was accepted and agreed (78 %). The majority of pediatricians felt that a more intense divulgation and information about AIT would be needed (90 %).

Conclusion

AIT is in general well known and accepted among PCP, although a more intense divulgation effort is required.

【 授权许可】

   
2015 Landi et al.

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【 参考文献 】
  • [1]Bendiks M, Kopp MV. The relationship between advances in understanding the microbiome and the maturing hygiene hypothesis. Curr Allergy Asthma Rep. 2013; 13:487-94.
  • [2]Lombardi C, Fiocchi A, Raffetti E, Donato F, Canonica GW, Passalacqua G et al.. Cross-sectional comparison of the characteristics of respiratory allergy in immigrants and Italian children. Pediatr Allergy Immunol. 2014; 25:473-80.
  • [3]Galassi C, Forastiere F, Biggeri A, Gabellini C, De Sario M, Ciccone G et al.. SIDRIA second phase: objectives, study design and methods. Epidemiol Prev. 2005; 29(suppl 1):24-31.
  • [4]Ker J, Hartert TV. The atopic march: what’s the evidence? Ann Allergy Asthma Immunol. 2009; 103:282-9.
  • [5]Linneberg A. The allergic march in early childhood and beyond. Clin Exp Allergy. 2008; 38:1419-21.
  • [6]Burgess JA, Lowe AJ, Matheson MC, Varigos G, Abramson MJ, Dharmage SC. Does eczema lead to asthma? J Asthma. 2009; 46:429-36.
  • [7]Gentile D, Bartholow A, Valovirta E, Scadding G, Skoner D. Current and future directions in pediatric allergic rhinitis. J Allergy Clin Immunol Pract. 2013; 1:214-26.
  • [8]Borres MP. Allergic rhinitis: more than just a stuffy nose. Acta Paediatr. 2009; 98:1088-92.
  • [9]Nota del segretariato generale del Consiglio dell’Unione Europea-Bruxelles, nov 17 2011 (22.11) (OR. en) 16709/11 SAN 239
  • [10]Passalacqua G. Specific immunotherapy: beyond the clinical scores. Ann Allergy Asthma Immunol. 2011; 107:401-6.
  • [11]Larenas-Linnemann D, Blaiss M, Van Bever HP, Compalati E, Baena-Cagnani CE. Pediatric sublingual immunotherapy efficacy: evidence analysis, 2009–2012. Ann Allergy Asthma Immunol. 2013; 110:402-15.
  • [12]Agostinis F, Foglia C, Landi M, Cottini M, Lombardi C, Canonica GW et al.. The safety of sublingual immunotherapy with one or multiple pollen allergens in children. Allergy. 2008; 63:1637-9.
  • [13]Pajno GB, Vita D, Caminiti L, Arrigo T, Lombardo F, Incorvaia C et al.. Children’s compliance with allergen immunotherapy according to administration routes. J Allergy Clin Immunol. 2005; 116:1380-1.
  • [14]Allergen immunotherapy : therapeutical vaccines for allergic diseases. Bousquet J, Lockey R, Malling HJ edts. Allergy. 1998; 53(suppl 52):3-15.
  • [15]Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A et al.. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen). Allergy. 2008; 63 Suppl 86:8-160.
  • [16]Canonica GW, Cox L, Pawankar R, Baena-Cagnani CE, Blaiss M et al.. Sublingual immunotherapy: World Allergy Organization position paper 2013 update. World Allergy Organ J. 2014; 7(1):6. BioMed Central Full Text
  • [17]Möller C, Dreborg S, Ferdousi HA, Halken S, Høst A et al.. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). J Allergy Clin Immunol. 2002; 109:251-6.
  • [18]Novembre E, Galli E, Landi F, Caffarelli C, Pifferi M, De Marco E et al.. Coseasonal sublingual immunotherapy reduces the development of asthma in children with allergic rhinoconjunctivitis. J Allergy Clin Immunol. 2004; 114:851-7.
  • [19]Marogna M, Tomassetti D, Bernasconi A, Colombo F, Massolo A, Businco AD et al.. Preventive effects of sublingual immunotherapy in childhood: an open randomized controlled study. Ann Allergy Asthma Immunol. 2008; 101:206-11.
  • [20]Lombardi C, Canonica GW, Passalacqua G. The perception of allergen-specific immunotherapy among chest physicians: an Italian survey. Eur Ann Allergy Clin Immunol. 2014; 46:132-6.
  • [21]Lombardi C, Bettoncelli G, Canonica GW, Passalacqua G. The perception of allergen-specific immunotherapy among Italian general practitioners. Eur Ann Allergy Clin Immunol. 2014; 46:83-6.
  • [22]Canonica GW, Baena Cagnani CE, Compalati E, Bohle B, Bonici S, Bousquet J et al.. 100 years of immunotherapy: the Monaco charter. under the high patronage of His Serene Highness Prince Albert II of Monaco. Int Arch Allergy Immunol. 2013; 160:346-9.
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