Effect of obstructive sleep apnea diagnosis on health related quality of life

Health and Quality of Life Outcomes

Giuseppe Insalaco¹  Oreste Marrone¹  Salvatore Romano¹  Anna Lo Bue¹  Adriana Salvaggio¹  Serena Iacono Isidoro¹ 

[1] National Research Council of Italy, Institute of Biomedicine and Molecular Immunology “A. Monroy”, Via Ugo La Malfa, 153, Palermo, 90146, Italy

关键词: Body mass index;    Hypoxemia;    Gender;    Diagnosis;    Quality of life;    Obstructive sleep apnea;   

Others  :  1209231
DOI  :  10.1186/s12955-015-0253-1

 received in 2015-02-11, accepted in 2015-04-30,  发布年份 2015

【 摘 要 】

Background

Perceived Health Related Quality of Life (HRQoL) is impaired in obstructive sleep apnea (OSA). To our knowledge, no study has analyzed the effect of OSA diagnosis communication on HRQoL. We evaluated self-perceived HRQoL in patients afferent to our sleep center, in order to examine the effect of the diagnosis disclosure on their HRQoL.

Methods

Two hundred ninety-seven consecutive outpatients (227 M) (mean age 54.1 ± 11.6 yrs, range 23–80 yrs) were evaluated, before first clinical visit and nocturnal diagnostic examination (Time A), and after diagnosis disclosure (Time B), with two self-reported questionnaires for HRQoL assessment: Psychological General Well-Being Index (PGWBI), consisting of anxiety, depressed mood, positive well-being, self-control, general health, vitality subscales, and 12-Item Short-Form Health Survey (SF-12), comprising Physical (PCS) and Mental Component Summaries (MCS).

Results

Comparison of mean HRQoL scores at Time A with reference values, showed worse scores. Mean PGWBI Total and subscales scores improved at Time B. Similar improvement was observed for SF-12 MCS (p = 0.0148), but nor for SF-12 PCS. At Time B, Anxiety, Depression and Well-being PGWBI subscales became similar to reference values, while the scores in the other PGWBI subscales and SF-12 remained worse. Comparison between males and females showed higher HRQoL values for males at both times. Score changes were independent from age, gender, BMI, AHI, TSat₉₀ and excessive daytime sleepiness.

Conclusions

Diagnosis communication improves patients’ HRQoL, regardless of the severity. Changes in HRQoL after diagnosis disclosure may be due to patients’ motivation for medical check and diagnostic expectations.

【 授权许可】

   
2015 Isidoro et al.; licensee BioMed Central.

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