One pot light assisted green synthesis, storage and antimicrobial activity of dextran stabilized silver nanoparticles

Journal of Nanobiotechnology

Syed Nasir Abbas Bukhari³  Riaz Ahmed¹  Muhammad Raza Shah²  Muhammad Nawaz Tahir⁵  Ibrahim Jantan³  Abdullah Shah⁴  Muhammad Ajaz Hussain⁴ 

[1] Centre for Advanced Studies in Physics (CASP), GC University, Lahore 54000, Pakistan;International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan;Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia;Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan;Institute of Inorganic and Analytical Chemistry, Johannes Guttenberg University of Mainz, Duesbergweg 10-14, Mainz 55128, Germany

关键词: Antimicrobial activity;    Diffused sun light;    Storage of nanoparticles;    Ag nanoparticles;   

Others  :  1139304
DOI  :  10.1186/s12951-014-0053-5

 received in 2014-10-15, accepted in 2014-11-14,  发布年份 2014

【 摘 要 】

Background

Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report green synthesis of silver nanoparticles (Ag NPs) mediated with dextran. Dextran was used as a stabilizer and capping agent to synthesize Ag NPs using silver nitrate (AgNO₃) under diffused sunlight conditions.

Results

UV–vis spectra of as synthesized Ag nanoparticles showed characteristic surface plasmon band in the range from ~405-452 nm. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) studies showed spherical Ag NPs in the size regime of ~50-70 nm. Face centered cubic lattice of Ag NPs was confirmed by powder X-ray diffraction (PXRD). FT-IR spectroscopy confirmed that dextran not only acts as reducing agent but also functionalizes the surfaces of Ag NPs to make very stable dispersions. Moreover, on drying, the solution of dextran stabilized Ag NPs resulted in the formation of thin films which were found stable over months with no change in the plasmon band of pristine Ag NPs. The antimicrobial assay of the as synthesized Ag NPs showed remarkable activity.

Conclusion

Being significantly active against microbes, the Ag NPs can be explored for antimicrobial medical devices.

【 授权许可】

   
2014 Hussain et al.; licensee BioMed Central Ltd.

【 图 表 】

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