Wildlife health investigations: needs, challenges and recommendations

BMC Veterinary Research

Marie-Pierre Ryser-Degiorgis¹ 

[1] Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Postfach 8466, CH-3001 Bern, Switzerland

关键词: Wildlife;    Tools;    Risk factors;    Strategies;    Surveillance;    Impediments;    Health;    Harmonization;    Definitions;    Collaboration;   

Others  :  1119415
DOI  :  10.1186/1746-6148-9-223

 received in 2013-05-07, accepted in 2013-10-30,  发布年份 2013

【 摘 要 】

In a fast changing world with growing concerns about biodiversity loss and an increasing number of animal and human diseases emerging from wildlife, the need for effective wildlife health investigations including both surveillance and research is now widely recognized. However, procedures applicable to and knowledge acquired from studies related to domestic animal and human health can be on partly extrapolated to wildlife. This article identifies requirements and challenges inherent in wildlife health investigations, reviews important definitions and novel health investigation methods, and proposes tools and strategies for effective wildlife health surveillance programs. Impediments to wildlife health investigations are largely related to zoological, behavioral and ecological characteristics of wildlife populations and to limited access to investigation materials. These concerns should not be viewed as insurmountable but it is imperative that they are considered in study design, data analysis and result interpretation. It is particularly crucial to remember that health surveillance does not begin in the laboratory but in the fields. In this context, participatory approaches and mutual respect are essential. Furthermore, interdisciplinarity and open minds are necessary because a wide range of tools and knowledge from different fields need to be integrated in wildlife health surveillance and research. The identification of factors contributing to disease emergence requires the comparison of health and ecological data over time and among geographical regions. Finally, there is a need for the development and validation of diagnostic tests for wildlife species and for data on free-ranging population densities. Training of health professionals in wildlife diseases should also be improved. Overall, the article particularly emphasizes five needs of wildlife health investigations: communication and collaboration; use of synergies and triangulation approaches; investments for the long term; systematic collection of metadata; and harmonization of definitions and methods.

【 授权许可】

   
2013 Ryser-Degiorgis; licensee BioMed Central Ltd.

【 图 表 】

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【 参考文献 】

• [1]Daszak P, Cunningham AA, Hyatt AD: Anthropogenic environmental change and the emergence of infectious diseases in wildlife. Acta Trop 2001, 78:103-116.
• [2]Jones KE, Patel NG, Levy MA, Storeygard A, Balk D, Gittleman JL, Daszak P: Global trends in emerging infectious diseases. Nature 2008, 451:990-993.
• [3]Belant JL, Deese AR: Importance of wildlife disease surveillance. Human-Wildl Interactions 2010, 4:165-169.
• [4]Artois M, Ben Jebara K, Warns-Petit E, Leighton FA: National wildlife health surveillance systems. In Animal health and biodiversity – preparing for the future (Compend OIE Global Conf Wildl). Paris, France: World Organization for Animal Health (OIE); 2012:133-142.
• [5]Artois M, Bengis R, Delahay RJ, Duchêne M-J, Duff JP, Ferroglio E, Gortázar C, Hutchings MR, Kock RA, Leighton FA, Mörner T, Smith GC: Wildlife disease surveillance and monitoring. In Management of disease in wild mammals. Tokyo, Japan: Springer; 2009:187-214.
• [6]WHO: Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19–22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100) and entered into force on 7 April 1948. 1946. http://www.who.int/about/definition/en/print.html webcite
• [7]Blood DC, Studdert VP: Comprehensive Veterinary Dictionary. 2nd edition. London, United Kingdom: W. B. Saunders; 1999.
• [8]Godlee F: What is health? BMJ 2011, 343:d4817.
• [9]Huber M, Knottnerus JA, Green L, van der Horst H, Jadad AR, Kromhout D, Leonard B, Lorig K, Loureiro MI, van der Meer JWM, Schnabel P, Smith R, Van Weel C, Smid H: How should we define health? BMJ 2011, 343:d4163.
• [10]Kindig D, Stoddart G: What is population health? Am J Public Health 2003, 93:380-383.
• [11]Martin C, Pastoret P-P, Brochier B, Humblet M-F, Saegerman C: A survey of the transmission of infectious diseases/infections between wild and domestic ungulates in Europe. Vet Res 2011, 42:70. BioMed Central Full Text
• [12]Delahay RJ, Smith GC, Hutchings MR: The science of wildlife disease management. In Management of disease in wild mammals. Tokyo, Japan: Springer; 2009:1-8.
• [13]Munson L, Terio KA, Ryser-Degiorgis MP, Lane EP, Courchamp F: Wild felid diseases: conservation implications and management strategies. In Biology and conservation of wild felids. Oxford, United Kingdom: Oxford University Press; 2010:237-259.
• [14]Pirofski L, Casadevall A: Q and A: What is a pathogen? A question that begs the point. BMC Biol 2012, 10:6. BioMed Central Full Text
• [15]Munson L, Terio KA, Kock R, Mlengeya T, Roelke ME, Dubovi E, Summers B, Sinclair ARE, Packer C: Climate extremes promote fatal co-infections during canine distemper epidemics in African lions. Plos One 2008, 3:e2545.
• [16]Acevedo-Whitehouse K, Duffus ALJ: Effects of environmental change on wildlife health. Philos Trans R Soc Lond B Biol Sci 2009, 364:3429-3438.
• [17]Martin LB, Hopkins WA, Mydlarz LD, Rohr JR: The effects of anthropogenic global changes on immune functions and disease resistance. Ann N Y Acad Sci 2010, 1195:129-148.
• [18]Woodford MH: Veterinary aspects of ecological monitoring: the natural history of emerging infectious diseases of humans, domestic animals and wildlife. Trop Anim Health Prod 2009, 41:1023-1033.
• [19]Mariner JC, Hendrickx S, Pfeiffer DU, Costard S, Knopf L, Okuthe S, Chibeu D, Parmley J, Musenero M, Pisang C, Zingeser J, Jones BA, Ali SN, Bett B, McLaws M, Unger F, Araba A, Mehta P, Jost CC: Integration of participatory approaches into surveillance systems. Rev Sci Tech OIE 2011, 30:653-659.
• [20]Leighton A: Surveillance of wild animal diseases in Europe. Rev Sci Tech OIE 1995, 14:819-830.
• [21]Stallknecht DE: Impediments to wildlife disease surveillance, research, and diagnostics. Curr Top Microbiol Immunol 2007, 315:445-461.
• [22]Sieber V, Ryser-Degiorgis M-P, Botteron C: A study of neurological diseases in farmed deer in Switzerland, with emphasis on chronic wasting disease. Eur J Wildl Res 2008, 54:189-192.
• [23]Sieber V, Robert N, Schybli M, Sager H, Miserez R, Engels M, Ryser-Degiorgis M-P: Causes of mortality and diseases in farmed deer in Switzerland. Vet Med Int 2010, 2010:684924.
• [24]Wu N, Abril C, Thomann A, Grosclaude E, Doherr MG, Boujon P, Ryser-Degiorgis M-P: Risk factors for contacts between wild boar and outdoor pigs in Switzerland and investigations on potential Brucella suis spill-over. BMC Vet Res 2012, 8:116. BioMed Central Full Text
• [25]Kelly TR, Sleeman JM: Morbidity and mortality of red foxes (Vulpes vulpes) and gray foxes (Urocyon cinereoargenteus) admitted to the Wildlife Center of Virginia, 1993–2001. J Wildl Dis 2003, 39:467-469.
• [26]Duncan C, Backus L, Lynn T, Powers B, Salman M: Passive, opportunistic wildlife disease surveillance in the Rocky Mountain Region, USA. Transbound Emerg Dis 2008, 55:308-314.
• [27]Randall NJ, Blitvich BJ, Blanchong JA: Efficacy of wildlife rehabilitation centers in surveillance and monitoring of pathogen activity: a case study with West Nile virus. J Wildl Dis 2012, 48:646-653.
• [28]Ryser-Degiorgis M-P: Causes of mortality and diseases of Eurasian lynx (Lynx lynx). In Iberian lynx ex-situ conservation: An interdisciplinary approach. Madrid, Spain: Fundación Biodiversidad; 2009:274-289.
• [29]Marreros N, Frey CF, Willisch CS, Signer C, Ryser-Degiorgis M-P: Coprological analyses on apparently healthy Alpine ibex (Capra ibex ibex) from two Swiss colonies. Vet Parasitol 2012, 186:382-389.
• [30]Ryser-Degiorgis M-P: Planning of veterinary supervision for translocation programmes of wild felids. In Iberian lynx ex-situ conservation: An interdisciplinary approach. Madrid, Spain: Fundación Biodiversidad; 2009:488-497.
• [31]Oleaga A, Casais R, Balseiro A, Espí A, Llaneza L, Hartasánchez A, Gortázar C: New techniques for an old disease: sarcoptic mange in the Iberian wolf. Vet Parasitol 2011, 181:255-266.
• [32]Arenas AJ, Gómez F, Salas R, Carrasco P, Borge C, Maldonado A, O’Brien DJ, Martínez-Moreno FJ: An evaluation of the application of infrared thermal imaging to the tele-diagnosis of sarcoptic mange in the Spanish ibex (Capra pyrenaica). Vet Parasitol 2002, 109:111-117.
• [33]Ryser-Degiorgis M-P, Capt S: Occurrence of sarcoptic mange in free-ranging wildlife in Switzerland. Mamm Biol 2003, 68:57-58.
• [34]Chen C-C, Pei KJ-C, Lai Y-C, Mortenson JA: Participatory epidemiology to assess sarcoptic mange in serow of Taiwan. J Wildl Dis 2012, 48:869-875.
• [35]Madslien K, Ytrehus B, Vikøren T, Malmsten J, Isaksen K, Hygen HO, Solberg EJ: Hair-loss epizootic in moose (Alces alces) associated with massive deer ked (Lipoptena cervi) infestation. J Wildl Dis 2011, 47:893-906.
• [36]Ryser-Degiorgis M-P, Ingold P, Tenhu H, Tébar AM, Ryser A, Giacometti M: Encounters between Alpine ibex, Alpine chamois and domestic sheep in the Swiss Alps. Hystrix 2002, 13:1-11.
• [37]Casaubon J, Vogt H-R, Stalder H, Hug C, Ryser-Degiorgis M-P: Bovine viral diarrhea virus in free-ranging wild ruminants in Switzerland: low prevalence of infection despite regular interactions with domestic livestock. BMC Vet Res 2012, 8:204. BioMed Central Full Text
• [38]Cutler SJ, Fooks AR, van der Poel WHM: Public health threat of new, reemerging, and neglected zoonoses in the industrialized world. Emerg Infect Dis 2010, 16:1-7.
• [39]Henning KJ: What is syndromic surveillance? MMWR 2004, 53(Suppl):5-11.
• [40]Warns-Petit E, Morignat E, Artois M, Calavas D: Unsupervised clustering of wildlife necropsy data for syndromic surveillance. BMC Vet Res 2010, 6:56. BioMed Central Full Text
• [41]Euzenat K: Causes de mortalité et de morbidité du chevreuil en Suisse: étude rétrospective (1992–2002). Nantes, France: Veterinary thesis. Ecole Nationale Vétérinaire de Nantes; 2004.
• [42]Patz JA, Daszak P, Tabor GM, Aguirre AA, Pearl M, Epstein J, Wolfe ND, Kilpatrick AM, Foufopoulos J, Molyneux D, Bradley DJ: Unhealthy landscapes: Policy recommendations on land use change and infectious disease emergence. Environ Health Perspect 2004, 112:1092-1098.
• [43]Schöning JM, Cerny N, Prohaska S, Wittenbrink MM, Smith NH, Bloemberg G, Pewsner M, Schiller I, Origgi FC, Ryser-Degiorgis M-P: Surveillance of bovine tuberculosis and risk estimation of a future reservoir formation in wildlife in Switzerland and Liechtenstein. Plos One 2013, 8(1):e54253.
• [44]Thulke H-H, Eisinger D, Freuling C, Fröhlich A, Globig A, Grimm V, Müller T, Selhorst T, Staubach C, Zips S: Situation-based surveillance: adapting investigations to actual epidemic situations. J Wildl Dis 2009, 45:1089-1103.
• [45]Zanoni RG, Kappeler A, Müller UM, Müller C, Wandeler AI, Breitenmoser U: [Rabies-free status of Switzerland following 30 years of rabies in foxes]. Schweiz Arch Tierheilkd 2000, 142:423-429.
• [46]Boadella M, Gortázar C, Acevedo P, Carta T, Martín-Hernando MP, de la Fuente J, Vicente J: Six recommendations for improving monitoring of diseases shared with wildlife: examples regarding mycobacterial infections in Spain. Eur J Wildl Res 2011, 57:697-706.
• [47]Casaubon J, Chaignat V, Vogt H-R, Michel AO, Thür B, Ryser-Degiorgis M-P: Survey of bluetongue virus infection in free-ranging wild ruminants in Switzerland. BMC Vet Res 2013, 9:166. BioMed Central Full Text
• [48]Fairbrother A, Locke LN, Hoff GL: Noninfectious diseases of wildlife. 2nd edition. Ames, Iowa, United States: Iowa University Press; 1996.
• [49]Belloy L, Janovsky M, Vilei EM, Pilo P, Giacometti M, Frey J: Molecular epidemiology of Mycoplasma conjunctivae in Caprinae: transmission across species in natural outbreaks. Appl Environ Microbiol 2003, 69:1913-1919.
• [50]Ryser-Degiorgis M-P, Bischof DF, Marreros N, Willisch C, Signer C, Filli F, Brosi G, Frey J, Vilei EM: Detection of Mycoplasma conjunctivae in the eyes of healthy, free-ranging Alpine ibex: possible involvement of Alpine ibex as carriers for the main causing agent of infectious keratoconjunctivitis in wild Caprinae. Vet Microbiol 2009, 134:368-374.
• [51]Mavrot F, Vilei EM, Marreros N, Signer C, Frey J, Ryser-Degiorgis M-P: Occurrence, quantification, and genotyping of Mycoplasma conjunctivae in wild Caprinae with and without infectious keratoconjunctivitis. J Wildl Dis 2012, 48:619-631.
• [52]Abril C, Thomann A, Brodard I, Wu N, Ryser-Degiorgis M-P, Frey J, Overesch G: A novel isolation method of Brucella species and molecular tracking of Brucella suis biovar 2 in domestic and wild animals. Vet Microbiol 2011, 150:405-410.
• [53]Hoberg EP, Polley L, Jenkins EJ, Kutz SJ: Pathogens of domestic and free-ranging ungulates: global climate change in temperate to boreal latitudes across North America. Rev Sci Tech OIE 2008, 27:511-528.
• [54]Harvell CD, Mitchell CE, Ward JR, Altizer S, Dobson AP, Ostfeld RS, Samuel MD: Climate warming and disease risks for terrestrial and marine biota. Science 2002, 296:2158-2162.
• [55]Kuiken T, Leighton FA, Fouchier RAM, LeDuc JW, Peiris JSM, Schudel A, Stöhr K, Osterhaus ADME: Pathogen surveillance in animals. Science 2005, 309:1680-1681.
• [56]Gortázar C, Ferroglio E, Höfle U, Frölich K, Vicente J: Diseases shared between wildlife and livestock: a European perspective. Eur J Wildl Res 2007, 53:241-256.
• [57]Garner TWJ, Walker S, Bosch J, Hyatt AD, Cunningham AA, Fisher MC: Chytrid fungus in Europe. Emerg Infect Dis 2005, 11:1639-1641.
• [58]Frey CF, Schuppers ME, Müller N, Ryser-Degiorgis MP, Gottstein B: Assessment of the prevalence of Trichinella spp. in red foxes and Eurasian lynxes from Switzerland. Vet Parasitol 2009, 159:295-299.
• [59]Lanfranchi P, Ferroglio E, Poglayen G, Guberti V: Wildlife veterinarian, conservation and public health. Vet Res Comm 2003, 27(Suppl 1):567-574.
• [60]Van Campen H, Rhyan J: The role of wildlife in diseases of cattle. Food Anim Pract 2010, 26:147-161.
• [61]Ryser-Degiorgis M-P, Jakubek E-B, Af Segerstad CH, Bröjer C, Mörner T, Jansson DS, Lundén A, Uggla A: Serological survey of Toxoplasma gondii infection in free-ranging Eurasian lynx (Lynx lynx) from Sweden. J Wildl Dis 2006, 42:182-187.
• [62]Miller MW, Conner MM: Epidemiology of chronic wasting disease in free-ranging mule deer: spatial, temporal, and demographic influences on observed prevalence patterns. J Wildl Dis 2005, 41:275-290.
• [63]Artois M, Bourhy H, Müller TF, Selhorst T, Smith GC: Lyssavirus infections. In Infectious diseases of wild mammals and birds in Europe. Oxford, United Kingdom: Wiley-Blackwell; 2012:86-98.
• [64]Origgi FC, Plattet P, Sattler U, Robert N, Casaubon J, Mavrot F, Pewsner M, Wu N, Giovannini S, Oevermann A, Stoffel MH, Gaschen V, Segner H, Ryser-Degiorgis M-P: Emergence of canine distemper virus strains with modified molecular signature and enhanced neuronal tropism leading to high mortality in wild carnivores. Vet Pathol 2012, 49:913-929.
• [65]Degiorgis M-P, Frey J, Abdo E-M, Schlatter Y, Reist S, Janovsky M, Giacometti M: An outbreak of infectious keratoconjunctivitis in Alpine chamois (Rupicapra r. rupicapra) in Simmental-Gruyères, Switzerland. Schweiz Arch Tierheilkd 2000, 142:520-527.
• [66]Marreros N, Hüssy D, Albini S, Frey CF, Abril C, Vogt H-R, Holzwarth N, Wirz-Dittus S, Friess M, Engels M, Borel N, Willisch CS, Signer C, Hoelzle LE, Ryser-Degiorgis M-P: Epizootiologic investigations of selected abortive agents in free-ranging Alpine ibex (Capra ibex ibex) in Switzerland. J Wildl Dis 2011, 47:530-543.
• [67]Lindström E, Mörner T: The spreading of sarcoptic mange among Swedish red foxes (Vulpes vulpes L) in relation to fox population dynamics. Rev Ecol - Terre Vie 1985, 40:211-216.
• [68]Guberti V, Newman SH: Guidelines on wild bird surveillance for highly pathogenic avian influenza H5N1 virus. J Wildl Dis 2007, 43:29-34.
• [69]Wobeser GA: Investigation and management of disease in wild animals. New York, United States: Plenum Publishing Corporation; 1994.
• [70]Siembieda JL, Kock RA, McCracken TA, Newman SH: The role of wildlife in transboundary animal diseases. Anim Health Res Rev/Conf of research workers in animal diseases 2011, 12:95-111.
• [71]Giacometti M, Janovsky M, Jenny H, Nicolet J, Belloy L, Goldschmidt-Clermont E, Frey J: Mycoplasma conjunctivae infection is not maintained in alpine chamois in eastern Switzerland. J Wildl Dis 2002, 38:297-304.
• [72]Hoby S, Schwarzenberger F, Doherr MG, Robert N, Walzer C: Steroid hormone related male biased parasitism in chamois, Rupicapra rupicapra rupicapra. Vet Parasitol 2006, 138:337-348.
• [73]Tryland M, Okeke MI, Af Segerstad CH, Mörner T, Traavik T, Ryser-Degiorgis M-P: Orthopoxvirus DNA in Eurasian lynx, Sweden. Emerg Infect Dis 2011, 17:626-632.
• [74]Perez JM, Ruiz-Martinez I, Granados JE, Soriguer RC, Fandos P: The dynamics of sarcoptic mange in the ibex population of Sierra Nevada in Spain - influence of climatic factors. J Wildl Res 1997, 2:86-89.
• [75]Kilpatrick AM, Chmura AA, Gibbons DW, Fleischer RC, Marra PP, Daszak P: Predicting the global spread of H5N1 avian influenza. Proc Nat Acad Sci USA 2006, 103:19368-19373.
• [76]Carpenter TE: The spatial epidemiologic (r)evolution: a look back in time and forward to the future. Spat Spatio-Temp Epidemiol 2011, 2:119-124.
• [77]Müller U, Kappeler A, Zanoni RG, Breitenmoser U: [The development of rabies in Switzerland landscape determines the spread of a wildlife epidemic]. Schweiz Arch Tierheilkd 2000, 142:431-438.
• [78]Lindström E: Pattern of spread and effects of sarcoptic mange among red fox populations in Sweden. In Global trends in wildlife management (Transactions of the 18th IUBG Congress). Krakow-Warszawa, Poland: Swiat Press; 1991:591-595.
• [79]Staubach C, Thulke HH, Tackmann K, Hugh-Jones M, Conraths FJ: Geographic information system-aided analysis of factors associated with the spatial distribution of Echinococcus multilocularis infections of foxes. Am J Trop Med Hyg 2001, 65:943-948.
• [80]Mavrot F, Zimmermann F, Vilei EM, Ryser-Degiorgis M-P: Is the development of infectious keratoconjunctivitis in Alpine ibex and Alpine chamois influenced by topographic features? Eur J Wildl Res 2012, 58:869-874.
• [81]Wu N, Abril C, Hinić V, Brodard I, Thür B, Fattebert J, Hüssy D, Ryser-Degiorgis M-P: Free-ranging wild boar: a disease threat to domestic pigs in Switzerland? J Wildl Dis 2011, 47:868-879.
• [82]Rossi L, Fraquelli C, Vesco U, Permunian R, Sommavilla GM, Carmignola G, Da Pozzo R, Meneguz PG: Descriptive epidemiology of a scabies epidemic in chamois in the Dolomite Alps, Italy. Eur J Wildl Res 2007, 53:131-141.
• [83]Okafor CC, Grooms DL, Bruning-Fann CS, Averill JJ, Kaneene JB: Descriptive epidemiology of bovine tuberculosis in Michigan (1975–2010): lessons learned. Vet Med Int 2011, 2011:874924.
• [84]Reperant LA, Fuckar NS, Osterhaus ADME, Dobson AP, Kuiken T: Spatial and temporal association of outbreaks of H5N1 influenza virus infection in wild birds with the 0 degrees C isotherm. Plos Pathog 2010, 6:e1000854.
• [85]Lachish S, Bonsall MB, Lawson B, Cunningham AA, Sheldon BC: Individual and population-level impacts of an emerging poxvirus disease in a wild population of great tits. Plos One 2012, 7:e48545.
• [86]Rhyan JC, Spraker TR: Emergence of diseases from wildlife reservoirs. Vet Pathol 2010, 47:34-39.
• [87]OIE: Training manual on wildlife Diseases and surveillance. Paris, France: World Organization for Animal Health (OIE); 2010.
• [88]Kock MD: Wildlife, people and development: veterinary contributions to wildlife health and resource management in Africa. Trop Anim Health Prod 1996, 28:68-80.
• [89]Ryser-Degiorgis M-P, Origgi FC: Wildlife health surveillance in Switzerland: current strategies and emerging diseases. In Proc Jt EWDA/WDA Conf, 22–27 July 2012. Lyon, France: VetAgro Sup; 2012:36.
• [90]Hofmann MA, Thür B, Vanzetti T, Schleiss W, Schmidt J, Griot C: [Classical swine fever in wild boars in Switzerland]. Schweiz Arch für Tierheilkd 1999, 141:185-190.
• [91]Frölich K, Grabitzky SE, Walzer C, Delahay RJ, Dorrestein GM, Hatt J-M: Zoo and wildlife medical education: a European perspective. J Vet Med Educ 2006, 33:401-407.
• [92]Woodford MH: Quarantine and health screening protocols for wildlife prior to translocation and release into the wild. France, United Kingdom, Switzerland: Office International des Epizooties, Care for the Wild, Veterinary Specialist Group/Species Survival Commission of the World Conservation Union, and European Association of Zoo and Wildlife Veterinarians; 2000.
• [93]Woodford MH, Keet DF, Bengis RG: Post-mortem procedures for wildlife veterinarians and field biologists. Office International des Epizooties, Care for the Wild, and Veterinary Specialist Group/Species Survival Commission of the World Conservation Union. 2000.
• [94]Wilesmith JW: Epidemiological methods for investigating wild animal reservoirs of animal disease. Rev Sci Tech OIE 1991, 10:205-214.
• [95]Schmidt-Posthaus H, Breitenmoser-Würsten C, Posthaus H, Bacciarini L, Breitenmoser U: Causes of mortality in reintroduced Eurasian lynx in Switzerland. J Wildl Dis 2002, 38:84-92.
• [96]Molinari-Jobin A, Molinari P, Breitenmoser-Würsten C, Breitenmoser U: Significance of lynx Lynx lynx predation for roe deer Capreolus capreolus and chamois Rupicapra rupicapra mortality in the Swiss Jura Mountains. Wildl Biol 2002, 8:109-115.
• [97]Alasaad S, Permunian R, Gakuya F, Mutinda M, Soriguer RC, Rossi L: Sarcoptic-mange detector dogs used to identify infected animals during outbreaks in wildlife. BMC Vet Res 2012, 8:110. BioMed Central Full Text
• [98]Hoby S, Robert N, Mathis A, Schmid N, Meli ML, Hofmann-Lehmann R, Lutz H, Deplazes P, Ryser-Degiorgis M-P: Babesiosis in free-ranging chamois (Rupicapra r. rupicapra) from Switzerland. Vet Parasitol 2007, 148:341-345.
• [99]Giovannini S, Pewsner M, Hüssy D, Hächler H, Ryser-Degiorgis M-P, Hirschheydt J, Von Origgi FC: Epidemic of salmonellosis in passerine birds in Switzerland with spillover to domestic cats. Vet Pathol 2013, 50:597-606.
• [100]Lawson B, Lachish S, Colvile KM, Durrant C, Peck KM, Toms MP, Sheldon BC, Cunningham AA: Emergence of a novel avian pox disease in British tit species. Plos One 2012, 7:e40176.
• [101]Hofmann MA, Renzullo S, Baumer A: Phylogenetic characterization of H5N1 highly pathogenic avian influenza viruses isolated in Switzerland in 2006. Virus Genes 2008, 37:407-413.
• [102]Ryser A, Scholl M, Zwahlen M, Oetliker M, Ryser-Degiorgis M-P, Breitenmoser U: A remote-controlled teleinjection system for the low-stress capture of large mammals. Wildl Soc Bull 2005, 33:721-730.
• [103]Curry PS, Elkin BT, Campbell M, Nielsen K, Hutchins W, Ribble C, Kutz SJ: Filter-paper blood samples for ELISA detection of Brucella antibodies in caribou. J Wildl Dis 2011, 47:12-20.
• [104]Batista Linhares M, Kuhnert P, Overesch G, Origgi FC, Segner H, Belloy L, Ryser-Degiorgis M-P: Epidemiological and pathological investigations on Mycoplasma hyopneumoniae infection in wild boar (Sus scrofa) in Switzerland. In Proc Jt EWDA/WDA Conf, 22–27 July 2012. Lyon, France: VetAgro Sup; 2012:58.
• [105]Keeler SP, Ferro PJ, Brown JD, Fang X, El-Attrache J, Poulson R, Jackwood MW, Stallknecht DE: Use of FTA sampling cards for molecular detection of avian influenza virus in wild birds. Avian Dis 2012, 56:200-207.
• [106]Jakubek E-B, Mattsson R, Mörner T, Mattsson JG, Gavier-Widén D: Potential application of serological tests on fluids from carcasses: detection of antibodies against Toxoplasma gondii and Sarcoptes scabiei in red foxes (Vulpes vulpes). Acta Vet Scand 2012, 54:13. BioMed Central Full Text
• [107]Frey CF, Schuppers ME, Eidam V, Boujon P, Waldvogel A, Gottstein B: Occurrence of Trichinella spp. in wild boar in Switzerland. Schweiz Arch Tierheilkd 2009, 151:485-489.
• [108]Boadella M, Gortázar C: Effect of haemolysis and repeated freeze-thawing cycles on wild boar serum antibody testing by ELISA. BMC Res Notes 2011, 4:498. BioMed Central Full Text
• [109]Tryland M, Handeland K, Bratberg A-M, Solbakk I-T, Oksanen A: Persistence of antibodies in blood and body fluids in decaying fox carcasses, as exemplified by antibodies against Microsporum canis. Acta Vet Scand 2006, 48:10. BioMed Central Full Text
• [110]Romero CH, Meade PN, Shultz JE, Chung HY, Gibbs EP, Hahn EC, Lollis G: Venereal transmission of pseudorabies viruses indigenous to feral swine. J Wildl Dis 2001, 37:289-296.
• [111]Hanaki K-I, Ike F, Hatakeyama R, Hirano N: Reverse transcription-loop-mediated isothermal amplification for the detection of rodent coronaviruses. J Virol Meth 2012, 187:222-227.
• [112]Lei F, Shi W: Prospective of genomics in revealing transmission, reassortment and evolution of wildlife-borne avian influenza A (H5N1) viruses. Curr Genomics 2011, 12:466-474.
• [113]Giacometti M, Nicolet J, Frey J, Krawinkler M, Meier W, Welle M, Johansson KE, Degiorgis MP: Susceptibility of alpine ibex to conjunctivitis caused by inoculation of a sheep-strain of Mycoplasma conjunctivae. Vet Microbiol 1998, 61:279-288.
• [114]Thrusfield M: Veterinary epidemiology. 3rd edition. Oxford, United Kingdom: Blackwell Publishing; 2007.
• [115]Meinkoth JH, Kocan AA: Feline cytauxzoonosis. Vet Clin North Am Small Anim Pract 2005, 35:89-101. vi
• [116]Schrenzel MD: Molecular epidemiology of mycobacteriosis in wildlife and pet animals. Exot Anim Pract 2012, 15:1-23.
• [117]Habermehl KH: Altersbestimmung bei Wild- und Pelztieren: Möglichkeiten und Methoden. 2nd edition. Paul Parey: Hamburg, Germany; 1985.
• [118]Nimmervoll H, Hoby S, Robert N, Lommano E, Welle M, Ryser-Degiorgis M-P: Pathology of sarcoptic mange in red foxes (Vulpes vulpes): macroscopic and histologic characterization of three disease stages. J Wildl Dis 2013, 49:91-102.
• [119]Butler D: Disease surveillance needs a revolution. Nature 2006, 440:6-7.