RESTORE: an exploratory trial of an online intervention to enhance self-efficacy to manage problems associated with cancer-related fatigue following primary cancer treatment: study protocol for a randomized controlled trial

Trials

Claire Foster¹  Lucy Yardley³  Peter W F Smith²  Alison Richardson⁷  Emma Ream⁴  Carl R May⁷  Christine M May¹  Claire Hulme⁶  Deborah Fenlon⁷  Jessica Corner⁷  Lynn Calman¹  Matthew Breckons⁵  Jo Armes⁴  Chloe Grimmett¹ 

[1] Macmillan Survivorship Research Group, Faculty of Health Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK;Southampton Statistical Sciences Research Institute, University of Southampton, Southampton, SO17 1BJ, UK;School of Psychology, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK;Florence Nightingale School of Nursing and Midwifery, King’s College London, James Clerk Maxwell Building, London, SE1 8WA, UK;Institute of Health & Society, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK;Leeds Institute of Health Sciences, Charles Thackrah Building, University of Leeds, 101 Clarendon Road, Leeds, LS2 9LJ, UK;Faculty of Health Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK

关键词: Self-management;    Self-efficacy;    Online;    Fatigue;    Cancer survivors;   

Others  :  1093636
DOI  :  10.1186/1745-6215-14-184

 received in 2013-04-23, accepted in 2013-06-04,  发布年份 2013

【 摘 要 】

Background

There are over 25 million people worldwide living with or beyond cancer and this number is increasing. Cancer survivors face a range of problems following primary treatment. One of the most frequently reported and distressing symptoms experienced by cancer survivors is fatigue. There is growing support for survivors who are experiencing problems after cancer treatment to engage in supported self-management. To date there is some evidence of effective interventions to manage fatigue in this population; however, to our knowledge there are no online resources that draw on this information to support self-management of fatigue. This paper describes the protocol for an exploratory randomized controlled trial of an online intervention to support self-management of cancer-related fatigue after primary cancer treatment.

Methods/design

This is a parallel-group two-armed (1:1) exploratory randomized controlled trial including 125 cancer survivors experiencing fatigue (scoring ≥4 on a unidimensional 11-point numeric rating scale for fatigue intensity) within five years of primary treatment completion with curative intent. Participants will be recruited from 13 NHS Trusts across the UK and randomized to either the online intervention (RESTORE), or a leaflet comparator (Macmillan Cancer Backup, Coping with Fatigue). The primary outcome is a change in Perceived Self-Efficacy for Fatigue Self-Management (as measured by the Perceived Self-Efficacy for Fatigue Self-Management Instrument). Secondary outcomes include impact on perception and experience of fatigue (measured by the Brief Fatigue Inventory), and quality of life (measured by the Functional Assessment of Cancer Therapy - General and the Personal Wellbeing Index). Outcome measures will be collected at baseline, 6 weeks (completion of intervention), and 3 months. Process evaluation (including telephone interviews with recruiting staff and participants) will determine acceptability of the intervention and trial processes.

Discussion

Data from this trial will be used to refine the intervention and contribute to the design of an effectiveness trial. This intervention will be expanded to address other cancer-related problems important to cancer survivors following primary cancer treatment.

Trial registration

ISRCTN67521059

【 授权许可】

   
2013 Grimmett et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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