Head & Face Medicine | |
Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case | |
Norbert R Kübler1  Stefan Braunstein2  André C Zimmermann1  Rita A Depprich1  Jörg GK Handschel1  | |
[1] Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University, Moorenstr. 5, D-40225 Düsseldorf, Germany;Department for Pathology, Heinrich-Heine-University, Moorenstr. 5, D-40225 Düsseldorf, Germany | |
关键词: review; adenomatoid odontogenic tumor; | |
Others : 827169 DOI : 10.1186/1746-160X-1-3 |
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received in 2005-03-25, accepted in 2005-08-24, 发布年份 2005 | |
【 摘 要 】
Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional information about AOT, all reports regarding AOT and cited in "pubmed" since 1990 onward were reviewed. AOT accounts for about 1% until 9% of all odontogenic tumors. It is predominantly found in young and female patients, located more often in the maxilla in most cases associated with an uneruppted permanent tooth. For radiological diagnose the intraoral periapical radiograph seems to be more useful than panoramic. However, AOT frequently resemble other odontogenic lesions such as dentigerous cysts or ameloblastoma. Immunohistochemically AOT is characterized by positive reactions with certain cytokeratins. Treatment is conservative and the prognosis is excellent. For illustration a rare case of an AOT in the mandible is presented.
【 授权许可】
2005 Handschel et al; licensee BioMed Central Ltd.
【 预 览 】
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【 参考文献 】
- [1]Steensland HS: Epithelioma adamantinum. J Exper Med 1905, 6:377-389.
- [2]Unal T, Cetingul E, Gunbay T: Peripheral adenomatoid odontogenic tumor: Birth of a term. J Clin Pediatr Dent 1995, 19:139-142.
- [3]Philipsen HP, Reichart PA: Adenomatoid odontogenic tumour: facts and figures. Oral Oncol 1998, 35:125-131.
- [4]Adebayo ET, Ajike SO, Adekeye EO: Odontogenic tumours in children and adolescents: a study of 78 Nigerian cases. J Craniomaxillofac Surg 2002, 30:267-272.
- [5]Stypulkowska J: Odontogenic tumors and neoplastic-like changes of the jaw bone. Clinical study and evaluation of treatment results. Folia Med Cracov 1998, 39:135-141.
- [6]Chattopadhyay A: Adenomatoid odontogenic tumour: Review of literature and report of 30 cases from India. Indian J Dent Res 1994, 5:89-95.
- [7]Mosqueda-Taylor A, Ledesma-Montes C, Caballero-Sandoval S, Portilla-Robertson J, Ruiz-Godoy Rivera LM, Meneses-Garcia A: Odontogenic tumors in Mexico: a collaboratibe retrospective study of 349 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997, 84:672-675.
- [8]Arotiba JT, Ogunbiyi JO, Obiechina AE: Odontogenic tumours: a 15-year review from Ibadan, Nigeria. Br J Oral Maxillofac Surg 1997, 35:363-367.
- [9]Buchner A, Sciubba JJ: Peripheral odontogenic tumours: a review. Oral Surg Oral Med Oral Pathol 1987, 63:688-697.
- [10]Konouchi H, Asaumi J, Yanagi Y, Hisatomi M, Kishi K: Adenomatoid odontogenic tumor: correlation of MRI with histopathological findings. Eur J Rad 2002, 44:19-23.
- [11]Philipsen HP, Reichart PA, Zhang KH, Nikai H, Yu QX: Adenomatoid odontogenic tumor: biologic profile based on 499 cases. J Oral Pathol Med 1991, 20:149-158.
- [12]Dare A, Yamaguchi A, Yoshiki S, Okano T: Limitation of panoramic radiography in diagnosing adenomatoid odontogenic tumors. Oral Surg Oral Med Oral Pathol 1994, 77:662-668.
- [13]Toida M, Hyodo I, Okuda T, Tatematsu N: Adenomatoid odontogenic tumor: report of two cases and survey of 126 cases in Japan. J Oral Maxillofac Surg 1990, 48:404-408.
- [14]Kramer IRH, Pindborg JJ, Shear M: WHO histological typing of odontogenic tumours. 2nd edition. Springer Verlag Berlin, Heidelberg, New York; 1992.
- [15]Philipsen HP, Reichart PA: The adenomatoid odontogenic tumour: ultrastructure of tumour cells and non-calcified amorphous masses. J Oral Pathol Med 1996, 25:491-496.
- [16]Takeda Y, Sato H, Satoh M, Nakamura S, Yamamoto H: Pigmented ameloblastic fibrodentinoma: a novel melanin-pigmented intraosseous odontogenic lesion. Virchows Arch 2000, 437:454-458.
- [17]Buchner A, David R, Carpenter W, Leider A: Pigmented lateral periodontal cyst and other pigmented odontogenic lesions. Oral Dis 1996, 2:299-302.
- [18]Larson A, Swartz K, Heikinheimo K: A case of multiple AOT-like jawbone lesions in a young patient-a new odontogenic entity? J Oral Pathol Med 2003, 32:55-62.
- [19]Crivelini MM, de Araujo VC, de Sousa SO, de Araujo NS: Cytokeratins in epithelia of odontogenic neoplasms. Oral Dis 2003, 9:1-6.
- [20]Abiko Y, Murata M, Ito Y, Taira T, Nishimura M, Arisue M, Inoue T, Shimono M, Kuboki Y, Kaku T: Immunhistochemical localization of amelogenin in human odontogenic tumors, using a polyclonal antibody against bovine amelogenin. Med Electron Microsc 2001, 34:185-189.
- [21]Takahashi H, Fujita S, Shibata Y, Yamaguchi A: Adenomatoid odontogenic tumour: immunohistochemical demonstration of transferring, ferritin and alpha-one-antitrypsin. J Oral Pathol Med 2001, 30:237-244.
- [22]Gao YH, Yang LJ, Yamaguchi A: Immunohistochemical demonstration of bone morphogenic protein in odontogenic tumors. J Oral Pathol Med 1997, 26:273-277.
- [23]Blumenthal NM, Mostofi R: Repair of an intrabony defect from an adenomatoid odontogenic tumor. J Periodontol 2000, 71:1637-1640.
- [24]Philipsen HP, Reichart PA, Nikai H: The adenomatoid odontogenic tumour (AOT): An update. Oral Medicine & Pathology 1997, 2:55-60.