期刊论文详细信息
Journal of Medical Case Reports
Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report
Ching-Chang Lee1  Wu-Hsien Kuo1  Ren-Jy Ben1  Mei-Yu Liu1  Chih-Chiang Wang1  Cheng-Hui Lin1  Shih-Chung Huang1  Chen-Yi Liao1 
[1] Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan
关键词: Symmetrical peripheral gangrene (SPG);    Severe acute pancreatitis;    Low volemic state;   
Others  :  1231235
DOI  :  10.1186/s13256-015-0688-3
 received in 2015-02-05, accepted in 2015-08-21,  发布年份 2015
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【 摘 要 】

Introduction

Symmetrical peripheral gangrene is an uncommon but devastating complication in critically ill patients, and it has a high mortality. It is seen in a wide variety of medical conditions, presenting as symmetrical gangrene of two or more extremities without large blood vessel obstruction.

Case presentation

We report a case of a 44-year-old Chinese man who was diagnosed with alcohol-related severe acute pancreatitis and presented with systemic inflammatory response syndrome and intractable vomiting. On the fourth day of admission, the patient developed cyanosis and gangrene of the fingers bilaterally. His cyanosis and gangrene did not resolve despite tapering of the vasopressor treatment. Gradually, his digital gangrene improved after administration of anti-platelet medication and pentoxifylline.

Conclusions

To the best of our knowledge, this is the first case report of symmetrical peripheral gangrene occurring after acute pancreatitis with successful resolution. We highlight the importance of prompt and aggressive fluid resuscitation and consideration of multiple treatment options to prevent a hypovolemic state caused by acute pancreatitis.

【 授权许可】

   
2015 Liao et al.

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【 参考文献 】
  • [1]Davis MP, Byrd J, Lior T, Rooke TW. Symmetrical peripheral gangrene due to disseminated intravascular coagulation. Arch Dermatol. 2001; 137:139-40.
  • [2]Johansen K, Hansen ST. Symmetrical peripheral gangrene (purpura fulminans) complicating pneumococcal sepsis. Am J Surg. 1993; 165:642-5.
  • [3]Hayes MA, Yau EH, Hinds CJ, Watson JD. Symmetrical peripheral gangrene: association with noradrenaline administration. Intensive Care Med. 1992; 18:433-6.
  • [4]Davis MD, Dy KM, Nelson S. Presentation and outcome of purpura fulminans associated with peripheral gangrene in 12 patients at Mayo Clinic. J Am Acad Dermatol. 2007; 57:944-56.
  • [5]Goodwin JN. Symmetrical peripheral gangrene. Arch Surg. 1974; 108:780-4.
  • [6]Davis MD. Peripheral symmetrical gangrene. Mayo Clin Proc. 2004; 79:914.
  • [7]Tripathy S, Rath B. Symmetric peripheral gangrene: catch it early! J Emerg Trauma Shock. 2010; 3:189-90.
  • [8]Sharma BD, Kabra SR, Gupta B. Symmetrical peripheral gangrene. Trop Doct. 2004; 34:2-4.
  • [9]Molos MA, Hall JC. Symmetrical peripheral gangrene and disseminated intravascular coagulation. Arch Dermatol. 1985; 121:1057-61.
  • [10]Bhalla A, Gupta S, Jain AP, Jajoo UN, Gupta OP, Kalantri SP. Blue toe syndrome: a rare complication of acute pancreatitis. JOP. 2003; 4:17-9.
  • [11]Lee SY, Ng KH, Sebastian MG. Arterio-pancreatic syndrome. Case Rep Gastroenterol. 2011; 5:17-21.
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