Put a tiger in your tank: the polyclad flatworm Maritigrella crozieri as a proposed model for evo-devo

EvoDevo

Bernhard Egger⁴  Maximilian J Telford¹  Gáspár Jékely²  Jürgen Berger²  Bartłomiej Tomiczek¹  Johannes Girstmair⁴  Kate A Rawlinson³  François Lapraz¹ 

[1] Department of Genetics, Evolution and Environment, University College London, London, UK;Max Planck Institute for Developmental Biology, Tübingen, Germany;Department of Biology, Dalhousie University, Halifax, NS, Canada;Department of Evolutionary Developmental Biology, Institute of Zoology, University of Innsbruck, Innsbruck, Austria

关键词: Turbellarians;    Transcriptome;    Stem cells;    Spiralians;    Regeneration;    Polyclad flatworms;    Planarians;    Neuropeptides;    Larvae;    Evolutionary and developmental biology;   

Others  :  817774
DOI  :  10.1186/2041-9139-4-29

 received in 2013-06-07, accepted in 2013-08-14,  发布年份 2013

【 摘 要 】

Polyclad flatworms are an early branching clade within the rhabditophoran Platyhelminthes. They provide an interesting system with which to explore the evolution of development within Platyhelminthes and amongst Spiralia (Lophotrochozoa). Unlike most other flatworms, polyclads undergo spiral cleavage (similar to that seen in some other spiralian taxa), they are the only free-living flatworms where development via a larval stage occurs, and they are the only flatworms in which embryos can be reared outside of their protective egg case, enabling embryonic manipulations. Past work has focused on comparing early cleavage patterns and larval anatomy between polyclads and other spiralians. We have selected Maritigrella crozieri, the tiger flatworm, as a suitable polyclad species for developmental studies, because it is abundant and large in size compared to other species. These characteristics have facilitated the generation of a transcriptome from embryonic and larval material and are enabling us to develop methods for gene expression analysis and immunofluorescence techniques. Here we give an overview of M. crozieri and its development, we highlight the advantages and current limitations of this animal as a potential evo-devo model and discuss current lines of research.

【 授权许可】

   
2013 Lapraz et al.; licensee BioMed Central Ltd.

【 图 表 】

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