Diagnostic Pathology | |
A large mediastinal benign myoepithelioma effacing the entire hemithorax: case report with literature review | |
Mehmood Khan1  Muhammad Muzzammil Edhi1  Naveen Faridi1  Amna Khurshid1  Atif Ali Hashmi1  | |
[1] Dhaka Medical College, Dhaka, Bangladesh | |
关键词: Mediastinum; Benign mixed tumor; Myoepithelioma; | |
Others : 1219331 DOI : 10.1186/s13000-015-0340-y |
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received in 2015-05-07, accepted in 2015-06-29, 发布年份 2015 | |
【 摘 要 】
Background
Myoepithelial neoplasms, although sometimes encountered in soft tissues are described very rarely in mediastinum and lung. We reported a rare case of such a tumor which was very large in size and not connected to respiratory tree.
Case presentation
A 24 year old male presented with blunt chest pain and respiratory distress. A CT scan was performed which showed large heterogeneously enhancing soft tissue mass occupying the left hemithorax. It measures 18.5 X 15.8 X 7.6. Thoracotomy with excision of the tumor was done. Operative findings include multilobulated and nodular large glistening white tumor located in anterior mediastinum adherent to parietal pleura and effacing the pulmonary parenchyma. However tumor was not connected or seems to originate from trachea or lung. Microscopic sections show neoplastic lesion composed of nests, cords and trabeculae of small to medium sized cells with round nuclei and clear cytoplasm. Background showed myxoid appearance with areas of cartilaginous differentiation. Immunohistochemical expression of CKAE1/AE3, p63, ASMA, S100 and GFAP favored the diagnosis of benign myoepithelioma.
Conclusion
Myoepithelial tumors are rare soft tissue tumors thought to arise from stem cells capable of divergent differentiation and occur anywhere in the body. Histopathologic recognition of these tumors is essential as these tumors may behave in a benign fashion despite large sizes.
【 授权许可】
2015 Hashmi et al.
【 预 览 】
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20150716030904905.pdf | 2918KB | download | |
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Fig. 2. | 168KB | Image | download |
Fig. 1. | 80KB | Image | download |
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