期刊论文详细信息
Irish Veterinary Journal
Pleural mesothelioma in a nine-month-old dog
Sule Yurdagul Ozsoy1  Zafer Ozyildiz3  Sevil Atalay Vural2 
[1] Department of Pathology, Faculty of Veterinary Medicine, Mustafa Kemal University, Hatay, Turkey;Department of Pathology, Faculty of Veterinary Medicine, Ankara University, 06110 Diskapi/Ankara, Turkey;Department of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey
关键词: Dog;    Pleura;    Mesothelioma;   
Others  :  1150455
DOI  :  10.1186/2046-0481-60-1-30
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【 摘 要 】

This paper reports on an unusual case of pleural epitheloid mesothelioma in a nine-month-old male, mixed breed dog. The dog was presented in-extremis and, on post mortem examination, multiple, exophytic, frequently pedunculated, yellowish-red, soft to firm masses ranging from 3 mm to 6 cm in diameter were diffusely distributed over, and attached to, the pericardial and parietal pleural surfaces. Microscopically, these masses consisted of round to partially polygonalshaped, anaplastic cells with minimal cytoplasm and hyperchromatic nuclei covering papillomatous projections or as part of more densely cellular masses. A supporting fibrovascular stroma and mitotic figures were also evident. Constituent tumour cells were labeled positively with antibodies against both vimentin and cytokeratin. In contrast, the same cells exhibited equivocal labeling with an antibody directed against calretinin antigen and did not label with antibodies against carcinoembryonic antigen (CEA) and milk fat globule-related antigen (MFGRA). Such tumours are rare in dogs, particularly in such a young animal.

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