Peritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus

Diagnostic Pathology

Michio Shimizu²  Shin-ichi Murata²  Atsushi Sasaki¹  Hidekazu Kayano¹  Koji Nagata²  Hiroshi Yamaguchi²  Takaya Ichimura²  Masanori Yasuda²  Keiichiro Uehara² 

[1] Department of Pathology, Saitama Medical University, Saitama, Japan;Department of Pathology, Saitama Medical University, International Medical Center, Saitama, Japan

关键词: uterine corpus;    squamous differentiation;    peritoneal keratin granuloma;    endometrioid adenocarcinoma;   

Others  :  808217
DOI  :  10.1186/1746-1596-6-104

 received in 2011-07-25, accepted in 2011-10-28,  发布年份 2011

【 摘 要 】

We present a 69-year-old woman with a chief complaint of postmenopausal bleeding. She was diagnosed as having an endometrioid adenocarcinoma by biopsy, and underwent a total abdominal hysterectomy. At the time of surgery, granulation tissue-like nodules were found on the peritoneal serosa of the uterus. In the intraoperative cytology of peritoneal washing, atypical cells were noted. The intraoperative frozen section of the peritoneal nodule revealed granulation tissue with proliferating mesothelial cells. Microscopic examination of the permanent section showed keratin granulomas without viable adenocarcinoma cells on the serosal surface of the ovaries, fallopian tubes and broad ligaments. Postoperative chemotherapy was administered. She has been alive with no evidence of recurrence for 6 months postoperatively. It should be noted that the prognosis of cases in peritoneal keratin granuloma without viable cancer cells is favorable, and that the histological examination is essential for its diagnosis.

Virtual Slides

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【 授权许可】

   
2011 Uehara et al; licensee BioMed Central Ltd.

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