Mapping quantitative trait loci affecting fatness and breast muscle weight in meat-type chicken lines divergently selected on abdominal fatness

Genetics Selection Evolution

Madeleine Douaire⁴  Alain Vignal⁸  Bernard Leclercq⁵  Sammy Aggrey²  Larry Cogburn⁷  Jean Simon⁵  Michel Sourdioux³  Yves Amigues⁶  André Neau⁹  Pascale Le Roy¹  Behnam Abasht⁴  Wilfrid Carré⁷  Frédérique Pitel⁸  Sandrine Lagarrigue⁴ 

[1] SGQA, Inra, 78352 Jouy-en-Josas, France;University of Georgia, Athens, GA 30602, USA;Gene+, 62134 Erin, France;UMR Inra-Agrocampus génétique animale, 35042 Rennes, France;Station de recherches avicoles, Inra, 37380 Nouzilly, France;Labogena, 78352 Jouy-en-Josas, France;Department of Animal and Food Sciences, University of Delaware,Newark, DE 19717, USA;Laboratoire de génétique cellulaire, Inra, 31326 Auzeville, France;Department of Animal Genetics, Inra, 78352 Jouy-en-Josas, France

关键词: chicken;    breast muscle;    abdominal fat;    quantitative trait locus;   

Others  :  1094163
DOI  :  10.1186/1297-9686-38-1-85

 received in 2005-02-28, accepted in 2005-08-18,  发布年份 2006

【 摘 要 】

Quantitative trait loci (QTL) for abdominal fatness and breast muscle weight were investigated in a three-generation design performed by inter-crossing two experimental meat-type chicken lines that were divergently selected on abdominal fatness. A total of 585 F₂ male offspring from 5 F₁ sires and 38 F₁ dams were recorded at 8 weeks of age for live body, abdominal fat and breast muscle weights. One hundred-twenty nine microsatellite markers, evenly located throughout the genome and heterozygous for most of the F₁ sires, were used for genotyping the F₂ birds. In each sire family, those offspring exhibiting the most extreme values for each trait were genotyped. Multipoint QTL analyses using maximum likelihood methods were performed for abdominal fat and breast muscle weights, which were corrected for the effects of 8-week body weight, dam and hatching group. Isolated markers were assessed by analyses of variance. Two significant QTL were identified on chromosomes 1 and 5 with effects of about one within-family residual standard deviation. One breast muscle QTL was identified on GGA1 with an effect of 2.0 within-family residual standard deviation.

【 授权许可】

   
2006 INRA, EDP Sciences