Effects of day-time exposure to different light intensities on light-induced melatonin suppression at night

Journal of Physiological Anthropology

Keisuke Hatae²  Ryunosuke Taketomi²  Ayaka Kubokawa²  Tomoaki Kozaki¹ 

[1] Faulty of Design, Kyushu University, 4-9-1 Shiobaru, Fukuoka city, Minami-ku, Japan;Graduate School of Design, Kyushu University, 4-9-1 Shiobaru, Fukuoka city, Minami-ku, Japan

关键词: Night-time;    Day-time;    Melatonin;    Light intensity;    Light;   

Others  :  1217318
DOI  :  10.1186/s40101-015-0067-1

 received in 2015-01-09, accepted in 2015-06-23,  发布年份 2015

【 摘 要 】

Background

Bright nocturnal light has been known to suppress melatonin secretion. However, bright light exposure during the day-time might reduce light-induced melatonin suppression (LIMS) at night. The effective proportion of day-time light to night-time light is unclear; however, only a few studies on accurately controlling both day- and night-time conditions have been conducted. This study aims to evaluate the effect of different day-time light intensities on LIMS.

Methods

Twelve male subjects between the ages of 19 and 23 years (mean ± S.D., 20.8 ± 1.1) gave informed consent to participate in this study. They were exposed to various light conditions (<10, 100, 300, 900 and 2700 lx) between the hours of 09:00 and 12:00 (day-time light conditions). They were then exposed to bright light (300 lx) again between 01:00 and 02:30 (night-time light exposure). They provided saliva samples before (00:55) and after night-time light exposure (02:30).

Results

A one-tailed paired t test yielded significant decrements of melatonin concentration after night-time light exposure under day-time dim, 100- and 300-lx light conditions. No significant differences exist in melatonin concentration between pre- and post-night-time light exposure under day-time 900- and 2700-lx light conditions.

Conclusions

Present findings suggest the amount of light exposure needed to prevent LIMS caused by ordinary nocturnal light in individuals who have a general life rhythm (sleep/wake schedule). These findings may be useful in implementing artificial light environments for humans in, for example, hospitals and underground shopping malls.

【 授权许可】

   
2015 Kozaki et al.

【 图 表 】

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