Increased EPA levels in serum phospholipids of humans after four weeks daily ingestion of one portion chicken fed linseed and rapeseed oil

Lipids in Health and Disease

Arne T Høstmark²  Malin Andersen¹  Therese J Mosti¹  Nicole F Nyquist¹  Anna Haug¹ 

[1] Department of Animal and Aquacultural Sciences, The Norwegian University of Life Sciences, P.O.BOX 5003, Ås, 1432, Norway;Section of Preventive Medicine and Epidemiology, University of Oslo, Blindern, P.O.BOX 113, Oslo, 0318, Norway

关键词: Soybean oil;    Rapeseed oil;    Linseed oil;    Feed;    Chicken meat;    Arachidonic acid;    EPA;    Serum phospholipids;    n-3 fatty acids;   

Others  :  1160228
DOI  :  10.1186/1476-511X-11-104

 received in 2012-06-15, accepted in 2012-08-12,  发布年份 2012

【 摘 要 】

Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans ingesting the chicken. Forty-six young healthy volunteers (age 20–29) were randomly allocated into two groups in a double-blind dietary intervention trial, involving ingestion of about 160 g chicken meat per day for 4 weeks. The ingested meat was either from chickens given a feed concentrate resembling the commercial chicken feed, containing 4% soybean oil (SO), or the meat was from chickens given a feed where the soybean oil had been replaced by 2% rapeseed oil plus 2% linseed oil (RLO).

Serum total cholesterol, LDL and HDL cholesterol, triacylglycerols, serum phospholipid fatty acid concentration, blood pressure, body weight and C-reactive protein were determined at baseline and post-intervention. In subjects consuming chicken meat from the RLO group there was a significantly (p < 0.001) increased concentration of EPA in serum phospholipids, and a reduced ratio between AA and EPA. The participants that had a low% of EPA + DHA in serum phospholipids (less than 4.6%), all increased their% of EPA + DHA after the four week intervention period when consuming the RLO chicken. No significant response differences in cholesterol, triacylglycerol, C-reactive protein, body weight or blood pressure were observed between the groups. This trial demonstrates that a simple change in chicken feed can have beneficial effects on amount of EPA and the AA/EPA ratio in human serum phospholipids.

【 授权许可】

   
2012 Haug et al.; licensee BioMed Central Ltd.

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