Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD)

Chinese Medicine

Vincent Kam-Wai Wong²  Jing-Fang Mo¹  Betty Yuen-Kwan Law² 

[1] School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China;State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China

关键词: qi;    Chinese Medicine;    saikosaponin;    Chaihu;    Autophagy;   

Others  :  1139167
DOI  :  10.1186/1749-8546-9-21

 received in 2014-03-04, accepted in 2014-09-08,  发布年份 2014

【 摘 要 】

Chaihu, prepared from the dried roots of Bupleurum Chinense DC (also known as bei Chaihu in Chinese) or Bupleurum scorzoneraefolium WILD (also known as nan Chaihu in Chinese), is a herbal medicine for harmonizing and soothing gan (liver) qi stagnation. Substantial pharmacological studies have been conducted on Chaihu and its active components (saikosaponins). One of the active components of Chaihu, saikosaponin-d, exhibited anticancer effects via autophagy induction. This article reviews the pharmacological findings for the roles of autophagy in the pharmacological actions of Chaihu and saikosaponins.

【 授权许可】

   
2014 Law et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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