International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol

BMC Veterinary Research

Holger A. Volk⁶  Andrea Tipold^1,13  Veronika M. Stein^1,13  Heidrun Potschka⁴  Michael Podell^1,17  Simon Platt^1,14  Jacques Penderis⁹  Akos Pakozdy^1,11  Edward E. Patterson⁷  Karen Muñana⁵  Kaspar Matiasek³  Andrea Fischer^1,16  Robyn G. Farqhuar²  Luisa De Risio¹  Sofie F. M. Bhatti^1,15  Mette Berendt⁸  Marjorie Milne^1,18  Jelena Jovanovik^1,12  Sam Long^1,18  Clare Rusbridge^1,10 

[1] Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK;Fernside Veterinary Centre, 205 Shenley Road, Borehamwood SG9 0TH, Hertfordshire, UK;Section of Clinical & Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, Munich, 80539, Germany;Department of Pharmacology, Toxicology and Pharmacy, Ludwig-Maximillians-University, Königinstr. 16, Munich, 80539, Germany;Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1052 William Moore Drive, Raleigh 27607, NC, USA;Department of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA, Hertfordshire, UK;University of Minnesota College of Veterinary Medicine, D426 Veterinary Medical Center, 1352 Boyd Avenue, St. Paul 55108, MN, USA;Department of Veterinary and Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark;Vet Extra Neurology, Broadleys Veterinary Hospital, Craig Leith Road, Stirling FK7 7LE, Stirlingshire, UK;School of Veterinary Medicine, Faculty of Health & Medical Sciences, University of Surrey, Guildford GU2 7TE, Surrey, UK;Clinical Unit of Internal Medicine Small Animals, University of Veterinary Medicine, Veterinärplatz 1, Vienna, 1210, Austria;Fitzpatrick Referrals, Halfway Lane, Eashing, Godalming GU7 2QQ, Surrey, UK;Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bünteweg 9, Hannover, 30559, Germany;College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens 30602, GA, USA;Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium;Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, Munich, 80539, Germany;Chicago Veterinary Neurology and Neurosurgery, 3123 N. Clybourn Avenue, Chicago 60618, IL, USA;University of Melbourne, 250 Princes Highway, Weibee 3015, VIC, Australia

关键词: Hippocampus;    Imaging;    Seizure;    Feline;    Canine;   

Others  :  1224257
DOI  :  10.1186/s12917-015-0466-x

 received in 2015-06-05, accepted in 2015-06-29,  发布年份 2015

【 摘 要 】

Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy. However, given that the diagnosis requires the exclusion of other differentials for seizures, the parameters for MRI examination should allow the detection of subtle lesions which may not be obvious with existing techniques. In addition, there are several differentials for idiopathic epilepsy in humans, for example some focal cortical dysplasias, which may only apparent with special sequences, imaging planes and/or particular techniques used in performing the MRI scan. As a result, there is a need to standardize MRI examination in veterinary patients with techniques that reliably diagnose subtle lesions, identify post-seizure changes, and which will allow for future identification of underlying causes of seizures not yet apparent in the veterinary literature.

There is a need for a standardized veterinary epilepsy-specific MRI protocol which will facilitate more detailed examination of areas susceptible to generating and perpetuating seizures, is cost efficient, simple to perform and can be adapted for both low and high field scanners. Standardisation of imaging will improve clinical communication and uniformity of case definition between research studies. A 6–7 sequence epilepsy-specific MRI protocol for veterinary patients is proposed and further advanced MR and functional imaging is reviewed.

【 授权许可】

   
2015 Rusbridge et al.

【 图 表 】

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