Periodontal conditions in patients with Marfan syndrome – a multicenter case control study

BMC Oral Health

Alexander Rahman¹  Werner Geurtsen¹  Oskar Bauss⁴  Maike Berner²  Yskert von Kodolitsch²  Eva Vahle-Hinz³  Bärbel Kahl-Nieke³  Christian Hauschild¹  Ingmar Staufenbiel¹ 

[1]Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany

[2]Center of Cardiology and Cardiovascular Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

[3]Department of Orthodontics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

[4]Private Practice, Hannover, Germany

关键词: Oral manifestations;    Dental conditions;    Attachment-loss;    Inflammation signs;    Periodontitis;    Periodontal conditions;    Marfan syndrome;   

Others  :  1121563
DOI  :  10.1186/1472-6831-13-59

 received in 2013-08-28, accepted in 2013-10-22,  发布年份 2013

【 摘 要 】

Background

Marfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibular joint have been well described by various authors. However, no data are available regarding a possible periodontal involvement of MFS. Hence, the aim of the present study was to investigate for the first time if MFS may increase the susceptibility to periodontitis.

Methods

A comprehensive periodontal examination including documentation of probing pocket depth, gingival recession, clinical attachment level, and bleeding on probing was conducted in all patients. In addition, dental conditions were assessed by determining the Index for Decayed, Missing and Filled Teeth (DMFT) and a self-administered questionnaire was filled out by patients. For statistical analysis, the unpaired t-Test was applied (level of significance: p < 0.05). Both groups were matched concerning well known periodontal risk factors like age, gender and smoking habits.

Results

82 participants, 51 patients with MFS (30 female and 21 male, mean age: 40.20 ± 15.35 years) and 31 sound controls (17 female and 14 male, mean age: 40.29 ± 13.94 years), were examined. All assessed periodontal and dental parameters were not significantly different between groups.

Conclusions

Based on our data, patients with MFS did not reveal a higher prevalence of periodontitis compared to the control group. However, Marfan patients showed a tendency to more inflammation signs, which can be explained by the crowded teeth. Therefore, a regular professional cleaning of the teeth is recommendable (i.e., 6 months intervals) in order to reduce the bacterial biofilm in the oral cavity and thus resulting in a decreased risk of systemic diseases, specifically endocarditis.

【 授权许可】

   
2013 Staufenbiel et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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