Vascular disease in women: comparison of diagnoses in hospital episode statistics and general practice records in England

BMC Medical Research Methodology

for the Million Women Study Collaborators¹  Valerie Beral¹  Angela Balkwill¹  Benjamin J Cairns¹  Dexter Canoy¹  Jane Green¹  F Lucy Wright¹ 

[1] Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Old Road Campus, Headington, Oxford, OX3 7LF, UK

关键词: Ischaemic heart disease;    Venous thromboembolism;    Pulmonary embolism;    Stroke;    Myocardial infarction;    Vascular disease;    Cohort study;    Validation;    Diagnosis;    Comparison;    Medical records;    Hospital records;    Hospital episode statistics;   

Others  :  1126595
DOI  :  10.1186/1471-2288-12-161

 received in 2012-03-28, accepted in 2012-10-17,  发布年份 2012

【 摘 要 】

Background

Electronic linkage to routine administrative datasets, such as the Hospital Episode Statistics (HES) in England, is increasingly used in medical research. Relatively little is known about the reliability of HES diagnostic information for epidemiological studies. In the United Kingdom (UK), general practitioners hold comprehensive records for individuals relating to their primary, secondary and tertiary care. For a random sample of participants in a large UK cohort, we compared vascular disease diagnoses in HES and general practice records to assess agreement between the two sources.

Methods

Million Women Study participants with a HES record of hospital admission with vascular disease (ischaemic heart disease [ICD-10 codes I20-I25], cerebrovascular disease [G45, I60-I69] or venous thromboembolism [I26, I80-I82]) between April 1^st 1997 and March 31^st 2005 were identified. In each broad diagnostic group and in women with no such HES diagnoses, a random sample of about a thousand women was selected for study. We asked each woman’s general practitioner to provide information on her history of vascular disease and this information was compared with the HES diagnosis record.

Results

Over 90% of study forms sent to general practitioners were returned and 88% of these contained analysable data. For the vast majority of study participants for whom information was available, diagnostic information from general practice and HES records was consistent. Overall, for 93% of women with a HES diagnosis of vascular disease, general practice records agreed with the HES diagnosis; and for 97% of women with no HES diagnosis of vascular disease, the general practitioner had no record of a diagnosis of vascular disease. For severe vascular disease, including myocardial infarction (I21-22), stroke, both overall (I60-64) and by subtype, and pulmonary embolism (I26), HES records appeared to be both reliable and complete.

Conclusion

Hospital admission data in England provide diagnostic information for vascular disease of sufficient reliability for epidemiological analyses.

【 授权许可】

   
2012 Wright et al.; licensee BioMed Central Ltd.

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