Prevention of peripherally inserted central line-associated blood stream infections in very low-birth-weight infants by using a central line bundle guideline with a standard checklist: a case control study: Prevention of PICC catheter related infections

BMC Pediatrics

Lili Wei⁵  Guirong Shen³  Ying Liu⁶  Qinglian Ji²  Chunling Zhao⁴  Wei Wang¹ 

[1] Departments of Neonatal, The Affiliated Hospital of Qingdao University, Qingdao 266003, China;Departments of Radiology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China;Departments of Humanities Nursing, Qingdao Medical College, Qingdao 266021, China;Departments of Central Supply Service, The Affiliated Hospital of Qingdao University, Qingdao 266003, China;Departments of Nursing, The Affiliated Hospital of Qingdao University, Qingdao 266003, China;Departments of Nursing, Weifang Nursing Vocational College, Qing zhou 262500, China

关键词: Catheter related infection;    PICC;    Very low birth weight infant;    Checklists;    Central line bundle;   

Others  :  1217906
DOI  :  10.1186/s12887-015-0383-y

 received in 2014-10-28, accepted in 2015-05-20,  发布年份 2015

【 摘 要 】

Backgrounds

Catheter-related infections (CRIs) are one of the severe complications of PICC placement. If treatment is not timely or correct, the incidence of infection and mortality rate can be high. A central line bundle (CLB) guideline was first proposed by the Institute for Healthcare Improvement, and included five key measures. Very low-birth-weight infants (VLBWIs) have a low immune response and indistinct symptoms after infection compared with other populations (Costa P, Kimura AF, de Vizzotto MP, de Castro TE, West A, Dorea E. Prevalence and reasons for non-elective removal of peripherally inserted central catheter in neonates. Rev Gaucha Enferm. 2012;33:126–33). Some reviews have focused on the effect and safety of a CLB in VLBWIs and its preventive effect on bacterial colonization and infection.

Methods

Fifty-seven VLBWIs who underwent PICC insertion at a hospital in Qingdao, China, between November 2012 and June 2013, and for whom a CLB guideline and a standard checklist were adopted, were included in the CLB group. In contrast, 53 VLBWIs who underwent PICC insertion, but for whom a CLB guideline and a standard checklist were not adopted, were included in the control group. The incidence of CRIs was compared between before and after the treatment.

Results

The incidence of infection showed a statistically significant reduction from 10.0 to 2.20 per 1000 catheter days in the control group (P < 0.05). The incidence of catheter-related bloodstream infections decreased from 3.1 to 0 per 1000 catheter days, and that of colonization infections decreased from 6.9 to 2.2 per 1000 catheter days (P < 0.05), both of which indicated a statistically significant difference. The indwelling catheter time was 24.8 ± 7.4 days in the control group and 31.9 ± 15.0 days in the study group (P < 0.05), and these values were significantly different.

Conclusion

The use of a CLB guideline with a standard checklist could be effective and feasible for preventing CRIs in VLBWIs and prolonging indwelling catheter time.

【 授权许可】

   
2015 Wang et al.

【 图 表 】

Fig. 1.

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