Population-based prevalence survey of tuberculosis in the Tigray region of Ethiopia

BMC Infectious Diseases

Abraham Aseffa³  Tewodros Haile¹  Rezene Berhe²  Ataklti Gebretsadik⁵  Tsigemariam Teklu⁵  Wondale Mekonnen³  Elena Hailu³  Fikre Enqueselassie²  Gebretsadik Berhe⁴ 

[1] Axum University, Axum, Ethiopia;School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia;Armauer Hansen Research Institute, Addis Ababa, Ethiopia;College of Veterinary Medicine, Mekelle University, Mekelle, Ethiopia;Tigray Health Bureau, Tigray, Ethiopia

关键词: Ethiopia;    Tigray region;    Pulmonary tuberculosis;    Cross-sectional;    Bacteriologically confirmed;   

Others  :  1145725
DOI  :  10.1186/1471-2334-13-448

 received in 2013-02-04, accepted in 2013-09-24,  发布年份 2013

【 摘 要 】

Background

Population based prevalence survey is an important epidemiological index to measure the burden of tuberculosis (TB) disease and monitor progress towards TB control in high burden countries like Ethiopia. This study was aimed to estimate the prevalence of bacteriologically confirmed pulmonary tuberculosis (PTB) in the Tigray region of Ethiopia.

Methods

Sixteen rural and urban villages were randomly selected in a stratified multistage cluster sampling. Individuals aged 15 years and older were screened by symptom inquiry for PTB. Those individuals who were symptomatic of PTB provided two sputum samples for smear microscopy, culture and molecular typing.

Results

The study covering 4,765 households screened a total of 12,175 individuals aged 15 years and above. The overall weighted prevalence of bacteriologically confirmed PTB in the Tigray region of Ethiopia was found to be 216/100,000 (95% CI: 202.08, 230.76) while the weighted prevalence of smear-positive PTB was 169/100,000 (95% CI: 155.53, 181.60). The prevalence of bacteriologically confirmed TB was higher amongst males (352/100 000; 95% CI: 339.05, 364.52) than females (162/100 000; 95% CI: 153.60, 171.17) and among rural (222/100,000; 95% CI: 212.77-231.53) as compared to urban residents (193/100,000; 95% CI: 183.39-203.59).

Conclusions

This study found a relatively higher prevalence smear-positive PTB in the region than in a same period nationwide survey and identified a significant number of undetected PTB cases. The urgency for improved TB case detection and intensified community awareness is emphasized.

【 授权许可】

   
2013 Berhe et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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