Calcified, minimally Fat-contained angiomyolipoma clinically indistinguishable from a renal cell carcinoma

BMC Nephrology

Tai-Lung Cha¹  Sun-Yran Chang¹  Dah-Shyong Yu¹  Guang-Huan Sun¹  Chih-Wei Tsao¹  En Meng¹  Sheng-Tang Wu¹  Shou-Hung Tang¹  Chin-Li Chen¹ 

[1] Division of Urology, Department of Surgery, Tri-Service General Hospital, No.325, Section 2, Cheng-Kung Road, Taipei 114, Taiwan, R.O.C

关键词: Renal cell carcinoma;    Radical nephrectomy;    Calcifications;    Angiomyolipoma;   

Others  :  1082879
DOI  :  10.1186/1471-2369-14-160

 received in 2012-09-30, accepted in 2013-07-08,  发布年份 2013

【 摘 要 】

Background

Angiomyolipomas are benign tumors of the kidney. Typical angiomyolipomas are usually recognized by identifying fat components before any intervention. On the contrary, solid renal masses without evident fatty components but containing calcifications on the computed tomography scan are suspicious for malignancy. However, as in this rare case, rules of diagnostic imaging are of exceptions.

Case presentation

A 40-year-old man presented with left flank pain. The plain X-ray showed multiple coarse calcifications of 4.0 x 3.2 cm in diameter on the left upper quadrant abdomen. Computed tomography scan further revealed a solid renal mass and inside the mass there were calcifications. The size of the tumor was 5.6 × 5.5 × 6.3 cm. We performed a radical nephrectomy, and the histopathology showed a minimally fat-contained angiomyolipoma of multiple calcifications. The patient was free of recurrence or metastases after a follow-up period of 3 years.

Conclusion

An angiomyolipoma containing calcification is rare. An angiomyolipoma with minimal fat concomitant with calcifications is an even rarer presentation. It is very difficult to differentiate a minimal-fat angiomyolipoma with calcifications from a renal cell carcinoma preoperatively. In such a circumstance, a well-planned partial nephrectomy may be optimal for the patient, regardless of the tumor size.

【 授权许可】

   
2013 Chen et al.; licensee BioMed Central Ltd.

【 图 表 】

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