Rational case management of malaria with a rapid diagnostic test, Paracheck Pf®, in antenatal health care in Bangui, Central African Republic

BMC Public Health

Jean Delmont⁶  Alain Le Faou³  Georges Soula⁶  Methode Moyen²  Nestor Madji²  Djibrine Djalle⁵  Luc Salva Heredeïbona⁴  Eugène Serdouma¹  Alexandre Manirakiza⁶ 

[1] Faculty of Health Sciences, University of Bangui, PO Box 1383, Bangui, Central African Republic;Malaria Programme Division, Ministry of Public Health, Population and AIDS Control, PO Box 883, Bangui, Central African Republic;Hôpital de Brabois Adultes, CHU de Nancy, 54511, Vandoeuvre-lès-Nancy Cedex, France;Ministry of Public Health, Population and AIDS Control, Castors Health Centre, Bangui, Central African Republic;Institut Pasteur de Bangui, Bangui, PO Box 923, Central African Republic;Centre de Formation et de Recherche en Médecine et Santé Tropicales, Faculté de Médecine Nord, 13015, Marseille, France

关键词: Pregnancy;    Malaria;    Rapid diagnostic test;   

Others  :  1163493
DOI  :  10.1186/1471-2458-12-482

 received in 2012-01-28, accepted in 2012-06-26,  发布年份 2012

【 摘 要 】

Background

Both treatment and prevention strategies are recommended by the World Health Organization for the control of malaria during pregnancy in tropical areas. The aim of this study was to assess use of a rapid diagnostic test for prompt management of malaria in pregnancy in Bangui, Central African Republic.

Methods

A cohort of 76 pregnant women was screened systematically for malaria with Paracheck_Pf® at each antenatal visit. The usefulness of the method was analysed by comparing the number of malaria episodes requiring treatment in the cohort with the number of prescriptions received by another group of pregnant women followed-up in routine antenatal care.

Results

In the cohort group, the proportion of positive Paracheck_Pf® episodes during antenatal clinics visits was 13.8%, while episodes of antimalarial prescriptions in the group which was followed-up routinely by antenatal personnel was estimated at 26.3%. Hence, the relative risk of the cohort for being prescribed an antimalarial drug was 0.53. Therefore, the attributable fraction of presumptive treatment avoided by systematic screening with Paracheck_Pf® was 47%.

Conclusions

Use of a rapid diagnostic test is useful, affordable and easy for adequate treatment of malaria in pregnant women. More powerful studies of the usefulness of introducing the test into antenatal care are needed in all heath centres in the country and in other tropical areas.

【 授权许可】

   
2012 Manirakiza et al.; licensee BioMed Central Ltd.

【 图 表 】

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