Validation of a triglyceride meter for use in pregnancy

BMC Research Notes

Leonie K Callaway²  H David McIntyre¹  Michael D’Emden²  Marloes Dekker Nitert²  Helen L Barrett² 

[1] Mater Medical Research Institute, Queensland, Australia;School of Medicine, The University of Queensland, St Lucia, Queensland, Australia

关键词: Point of care;    Diabetes;    Pregnancy;    Triglycerides;   

Others  :  1127396
DOI  :  10.1186/1756-0500-7-679

 received in 2014-03-03, accepted in 2014-09-15,  发布年份 2014

【 摘 要 】

Background

Elevated maternal triglycerides have been associated with adverse pregnancy outcomes including an increased risk of preeclampsia and macrosomia. A valid triglyceride meter would allow the examination of maternal postprandial triglycerides in a systematic manner. A non-fasting venous and two capillary measurements (using the Roche Accutrend® Plus meter) of triglycerides were measured in 40 participants at a mean of 36 weeks gestation.

Findings

The two methods were highly correlated (r = 0.89, P <0.0001), and the distributions were similar (mean difference 0.01 mmol/L (SD 0.47)), t = 0.18, P =0.86). Passing Bablok equation was: y = −0.01 + 0.98 × [95% CI intercept −0.51 – 0. 38; 95% CI slope 0.85-1.15). The estimated bias was −0.01 mmol/L (95% CI −0.93 – 0.91)).

Conclusions

This study demonstrated the Accutrend® Plus meter provides results that correlate strongly with the reference method, with low bias, when used in late pregnancy.

【 授权许可】

   
2014 Barrett et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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