期刊论文详细信息
BMC Psychiatry
The effects of motivational interviewing on patients with comorbid substance use admitted to a psychiatric emergency unit - a randomised controlled trial with two year follow-up
Gunnar Morken4  Pål Romundstad2  Solveig Klæbo Reitan5  Christine Østensen1  Johan Håkon Bjørngaard3  Gunnhild Bagøien5 
[1] Østmarka Department of Psychiatry, St. Olav University Hospital, Trondheim, Norway;Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway;Forensic Department and Research Centre Bröset, St. Olav University Hospital Trondheim, Norway;Department of Research and Development, Psychiatry, St. Olav University Hospital, P O Box 3008 Lade, Trondheim, NO-7441, Norway;Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
关键词: Hospitalisation;    Substance abuse;    Comorbidity;    Psychiatric emergency services;    Motivational interview;   
Others  :  1124101
DOI  :  10.1186/1471-244X-13-93
 received in 2012-06-26, accepted in 2013-03-12,  发布年份 2013
PDF
【 摘 要 】

Background

The prevalence of substance use in people acutely admitted to in-patient psychiatric wards is high and the patients` duration of stay is limited. Motivational interviewing is a method with evidence based effect in short interventions. The aims of the present study were to compare the effects of 2 sessions of motivational interviewing and treatment as usual (intervention group) with treatment as usual only (control group) on adult patients with comorbid substance use admitted to a psychiatric in-patient emergency unit.

Methods

This was an open randomised controlled trial including 135 patients where substance use influenced the admittance. After admission and assessments, the patients were allocated to the intervention group (n = 67) or the control group (n = 68). The primary outcome was self-reported days per month of substance use during the last 3 months at 3, 6, 12 and 24 months after inclusion. Data was analysed with a multilevel linear repeated measures regression model.

Results

Both groups reduced substance use during the first 12 months with no substantial difference between the 2 groups. At 2 year follow-up, the control group had increased their substance use with 2.4 days (95% confidence interval (CI) –1.5 to 6.3), whereas the intervention group had reduced their monthly substance use with 4.9 days (95% CI 1.2 to 8.6) compared to baseline. The 2 year net difference was 7.3 days of substance use per month (95% CI 1.9 to 12.6, p < 0.01) in favour of the intervention group.

Conclusions

The present study suggests that 2 sessions of motivational interviewing to patients with comorbid substance use admitted to a psychiatric emergency unit reduce substance use frequency substantially at 2 year follow-up.

Trial registration

ClinicalTrials.gov Identifier: NCT00184223

【 授权许可】

   
2013 Bagøien et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150216060928575.pdf 256KB PDF download
Figure 2. 25KB Image download
Figure 1. 141KB Image download
【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】
  • [1]Regier DA, Farmer ME, Rae DS, Locke BZ, Keith SJ, Judd LL, Goodwin FK: Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA 1990, 264:2511-2518.
  • [2]Lejoyeux M, Boulenguiez S, Fichelle A, McLoughlin M, Claudon M, Ades J: Alcohol dependence among patients admitted to psychiatric emergency services. Gen Hosp Psychiatry 2000, 22:206-212.
  • [3]Flovig JC, Vaaler AE, Morken G: Substance use at admission to an acute psychiatric department. Nord J Psychiatry 2009, 63:113-119.
  • [4]Lehman AF, Myers CP, Corty E, Thompson JW: Prevalence and patterns of "dual diagnosis" among psychiatric inpatients. Compr Psychiatry 1994, 35:106-112.
  • [5]Drake RE, Wallach MA: Substance abuse among the chronic mentally ill. Hosp Community Psychiatry 1989, 40:1041-1046.
  • [6]Rosen CS, Kuhn E, Greenbaum MA, Drescher KD: Substance abuse-related mortality among middle-aged male VA psychiatric patients. Psychiatr Serv 2008, 59:290-296.
  • [7]Soyka M: Substance misuse, psychiatric disorder and violent and disturbed behaviour. Br J Psychiatry 2000, 176:345-350.
  • [8]Swofford CD, Kasckow JW, Scheller-Gilkey G, Inderbitzin LB: Substance use: a powerful predictor of relapse in schizophrenia. Schizophr Res 1996, 20:145-151.
  • [9]Ries RK, Russo J, Wingerson D, Snowden M, Comtois KA, Srebnik D, Roy-Byrne P: Shorter hospital stays and more rapid improvement among patients with schizophrenia and substance disorders. Psychiatr Serv 2000, 51:210-215.
  • [10]Vaaler AE, Morken G, Flovig JC, Iversen VC, Linaker OM: Substance abuse and recovery in a Psychiatric Intensive Care Unit. Gen Hosp Psychiatry 2006, 28:65-70.
  • [11]Miller WR, Rollnick S: Motivational interviewing: preparing people for change. 2nd edition. New York: Guilford Press; 2002.
  • [12]Martins RK, McNeil DW: Review of Motivational Interviewing in promoting health behaviors. Clin Psychol Rev 2009, 29:283-293.
  • [13]Smedslund G, Berg RC, Hammerstrom KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K: Motivational interviewing for substance abuse. Cochrane Database Syst Rev 2011., 5CD008063
  • [14]Burke BL, Arkowitz H, Menchola M: The efficacy of motivational interviewing: a meta-analysis of controlled clinical trials. J Consult Clin Psychol 2003, 71:843-861.
  • [15]Lundahl BW, Kunz C, Brownell C, Tollefson D, Burke BL: A Meta-analysis of Motivational Interviewing:Twenty-five years of empirical studies. Res Soc Work Pract 2010, 20:137-160.
  • [16]Kallestad H, Valen J, McCullough L, Svartberg M, Hoglend P, Stiles TC: The relationship between insight gained during therapy and long-term outcome in short-term dynamic psychotherapy and cognitive therapy for cluster C personality disorders. Psychotherapy research: journal of the Society for Psychotherapy Research 2010, 20:526-534.
  • [17]Baker A, Lewin T, Reichler H, Clancy R, Carr V, Garrett R, Sly K, Devir H, Terry M: Evaluation of a motivational interview for substance use within psychiatric in-patient services. Addiction 2002, 97:1329-1337.
  • [18]Baker A, Lewin T, Reichler H, Clancy R, Carr V, Garrett R, Sly K, Devir H, Terry M: Motivational interviewing among psychiatric in-patients with substance use disorders. Acta Psychiatr Scand 2002, 106:233-240.
  • [19]Drake RE, O'Neal EL, Wallach MA: A systematic review of psychosocial research on psychosocial interventions for people with co-occurring severe mental and substance use disorders. J Subst Abuse Treat 2008, 34:123-138.
  • [20]Horsfall J, Cleary M, Hunt GE, Walter G: Psychosocial treatments for people with co-occurring severe mental illnesses and substance use disorders (dual diagnosis): a review of empirical evidence. Harv Rev Psychiatry 2009, 17:24-34.
  • [21]Baker AL, Hides L, Lubman DI: Treatment of cannabis use among people with psychotic or depressive disorders: a systematic review. J Clin Psychiatry 2010, 71:247-254.
  • [22]Barrowclough C, Haddock G, Wykes T, Beardmore R, Conrod P, Craig T, Davies L, Dunn G, Eisner E, Lewis S, Moring J, Steel C, Tarrier N: Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: randomised controlled trial. BMJ 2010, 341:c6325.
  • [23]Martino S, Carroll KM, Nich C, Rounsaville BJ: A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders. Addiction 2006, 101:1479-1492.
  • [24]Baker AL, Hiles SA, Thornton LK, Hides L, Lubman DI: A systematic review of psychological interventions for excessive alcohol consumption among people with psychotic disorders. Acta Psychiatr Scand 2012, 126:243-255.
  • [25]Baker AL, Thornton LK, Hiles S, Hides L, Lubman DI: Psychological interventions for alcohol misuse among people with co-occurring depression or anxiety disorders: A systematic review. J Affect Disord 2012, 139:217-229.
  • [26]Bagoien G, Morken G, Zahlsen K, Aamo T, Spigset O: Evaluation of a urine on-site drugs of abuse screening test in patients admitted to a psychiatric emergency unit. J Clin Psychopharmacol 2009, 29:248-254.
  • [27]American Psychiatric Association: Diagnostic and statistical manual of mental disorders: DSM-IV. 4th edition. Washington, D.C: APA; 1994.
  • [28]Pedersen G, Hagtvet KA, Karterud S: Generalizability studies of the Global Assessment of Functioning-Split version. Compr Psychiatry 2007, 48:88-94.
  • [29]World Health Organization: The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. Geneva: WHO; 1993.
  • [30]Hulse GK, Tait RJ: Six-month outcomes associated with a brief alcohol intervention for adult in-patients with psychiatric disorders. Drug Alcohol Rev 2002, 21:105-112.
  • [31]Miller WR, Yahne CE, Tonigan JS: Motivational interviewing in drug abuse services: a randomized trial. J Consult Clin Psychol 2003, 71:754-763.
  • [32]Rabe-Hesketh S, Skrondal A: Multilevel and longitudinal modeling using Stata. 2nd edition. College Station, Texas: Stata Press; 2008.
  • [33]Wood AM, White IR, Thompson SG: Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals. Clinical trials (London, England) 2004, 1:368-376.
  • [34]Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P: Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med 2008, 148:295-309.
  • [35]Schermer CR, Moyers TB, Miller WR, Bloomfield LA: Trauma center brief interventions for alcohol disorders decrease subsequent driving under the influence arrests. J Trauma 2006, 60:29-34.
  • [36]Baer JS, Kivlahan DR, Blume AW, McKnight P, Marlatt GA: Brief intervention for heavy-drinking college students: 4-year follow-up and natural history. Am J Public Health 2001, 91:1310-1316.
  • [37]Hettema J, Steele J, Miller WR: Motivational interviewing. Annu Rev Clin Psychol 2005, 1:91-111.
  • [38]Bonsack C, Camus D, Kaufmann N, Aubert AC, Besson J, Baumann P, Borgeat F, Gillet M, Eap CB: Prevalence of substance use in a Swiss psychiatric hospital: interview reports and urine screening. Addict Behav 2006, 31:1252-1258.
  文献评价指标  
  下载次数:7次 浏览次数:8次