Determining the prevalence and predictors of sleep disordered breathing in patients with chronic heart failure: rationale and design of the SCHLA-HF registry

BMC Cardiovascular Disorders

Karl Wegscheider³  Helmut Teschler⁵  Erland Erdmann⁶  Andrea Graml¹  Michael Arzt²  Olaf Oldenburg⁴  Holger Woehrle¹ 

[1] ResMed Science Center, Martinsried, Germany;Schlafmedizinisches Zentrum, Klinik und Poliklinik für Innere Medizin II, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany;Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany;Department of Pneumology, Respiratory and Sleep Medicine, Ruhrlandklinik, University Clinic Essen, Essen, Germany;Clinic III for Internal Medicine, Heart Center University Hospital Cologne, Cologne, Germany

关键词: Predictors;    Cheyne-Stokes respiration;    Central sleep apnea;    Obstructive sleep apnea;    Sleep-disordered breathing;    Heart failure;    Prevalence;    Registry;   

Others  :  855187
DOI  :  10.1186/1471-2261-14-46

 received in 2013-07-05, accepted in 2014-04-04,  发布年份 2014

【 摘 要 】

Background

The objective of the SCHLA-HF registry is to investigate the prevalence of sleep-disordered breathing (SDB) in patients with chronic heart failure with reduced left ventricular systolic function (HF-REF) and to determine predictors of SDB in such patients.

Methods

Cardiologists in private practices and in hospitals in Germany are asked to document patients with HF-REF into the prospective SCHLA-HF registry if they meet predefined inclusion and exclusion criteria. Screening was started in October 2007 and enrolment was completed at the end of May 2013. After enrolment in the registry, patients are screened for SDB. SDB screening is mainly undertaken using the validated 2-channel ApneaLink™ device (nasal flow and pulse oximetry; ResMed Ltd., Sydney, Australia). Patients with a significant number of apneas and hypopneas per hour recording time (AHI ≥15/h) and/or clinical symptoms suspicious of SDB will be referred to a cooperating sleep clinic for an attended in-lab polysomnography with certified scoring where the definite diagnosis and, if applicable, the differentiation between obstructive and central sleep apnea will be made. Suggested treatment will be documented.

Discussion

Registries play an important role in facilitating advances in the understanding and management of cardiovascular disease. The SCHLA-HF registry will provide consistent data on a large group of patients with HF-REF that will help to answer questions on the prevalence, risk factors, gender differences and stability of SDB in these patients by cross-sectional analyses. Further insight into the development of SDB will be gained by extension of the registry to include longitudinal data.

【 授权许可】

   
2014 Woehrle et al.; licensee BioMed Central Ltd.

【 图 表 】

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