期刊论文详细信息
BMC Psychiatry
Attention deficit/hyperactivity disorders with co-existing substance use disorder is characterized by early antisocial behaviour and poor cognitive skills
Tatja Hirvikoski2  Sven Bölte2  Jussi Jokinen1  Berit Bihlar Muld2 
[1] Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden;Department of Women’s and Children’s Health, Karolinska Institute, Pediatric Neuropsychiatry Unit, Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Stockholm, Gävlegatan 22B, SE-113 30, Sweden
关键词: Cognition;    Adults;    Compulsory care;    Co-morbidity;    SUD;    ADHD;   
Others  :  1123860
DOI  :  10.1186/1471-244X-13-336
 received in 2013-02-22, accepted in 2013-12-06,  发布年份 2013
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【 摘 要 】

Background

Attention Deficit/Hyperactivity Disorder (ADHD) is associated with an increased risk of co-existing substance abuse. The Swedish legislation on compulsory healthcare can be applied to persons with severe substance abuse who can be treated involuntarily during a period of six months. This context enables a reliable clinical assessment of ADHD in individuals with severe substance use disorder (SUD).

Methods

In the context of compulsory care for individuals with severe SUD, male patients were assessed for ADHD, co-morbid psychiatric symptoms, psychosocial background, treatment history, and cognition. The data from the ADHD/SUD group (n = 60) was compared with data from (1) a group of individuals with severe substance abuse without known ADHD (SUD group, n = 120), as well as (2) a group with ADHD from an outpatient psychiatric clinic (ADHD/Psych group, n = 107).

Results

Compared to the general SUD group in compulsory care, the ADHD/SUD group had already been significantly more often in compulsory care during childhood or adolescence, as well as imprisoned more often as adults. The most common preferred abused substance in the ADHD/SUD group was stimulant drugs, while alcohol and benzodiazepine abuse was more usual in the general SUD group. Compared to the ADHD/Psych group, the ADHD/SUD group reported more ADHD symptoms during childhood and performed poorer on all tests of general intellectual ability and executive functions.

Conclusions

The clinical characteristics of the ADHD/SUD group differed from those of both the SUD group and the ADHD/Psych group in several respects, indicating that ADHD in combination with SUD is a particularly disabling condition. The combination of severe substance abuse, poor general cognitive ability, severe psychosocial problems, including indications of antisocial behaviour, and other co-existing psychiatric conditions should be considered in treatment planning for adults with ADHD and SUD.

【 授权许可】

   
2013 Bihlar Muld et al.; licensee BioMed Central Ltd.

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