Treatment non-adherence in pediatric long-term medical conditions: systematic review and synthesis of qualitative studies of caregivers’ views

BMC Pediatrics

Sally Wyke¹  Adam WA Geraghty⁴  Lucy Yardley⁴  Nicola Ring²  Miriam Santer³ 

[1] The University of Glasgow, Glasgow, UK;The University of Stirling, Stirling, UK;Aldermoor Health Centre, The University of Southampton, Aldermoor Close, SO16 5ST, Southampton, UK;The University Of Southampton, Southampton, UK

关键词: Caregivers;    Long-term conditions;    Medication adherence;    Child health;    Qualitative synthesis;    Qualitative research;   

Others  :  1138979
DOI  :  10.1186/1471-2431-14-63

 received in 2013-06-07, accepted in 2014-02-24,  发布年份 2014

【 摘 要 】

Background

Non-adherence to prescribed treatments is the primary cause of treatment failure in pediatric long-term conditions. Greater understanding of parents and caregivers’ reasons for non-adherence can help to address this problem and improve outcomes for children with long-term conditions.

Methods

We carried out a systematic review and thematic synthesis of qualitative studies. Medline, Embase, Cinahl and PsycInfo were searched for relevant studies published in English and German between 1996 and 2011. Papers were included if they contained qualitative data, for example from interviews or focus groups, reporting the views of parents and caregivers of children with a range of long-term conditions on their treatment adherence. Papers were quality assessed and analysed using thematic synthesis.

Results

Nineteen papers were included reporting 17 studies with caregivers from 423 households in five countries. Long-term conditions included; asthma, cystic fibrosis, HIV, diabetes and juvenile arthritis. Across all conditions caregivers were making on-going attempts to balance competing concerns about the treatment (such as perceived effectiveness or fear of side effects) with the condition itself (for instance perceived long-term threat to child). Although the barriers to implementing treatment regimens varied across the different conditions (including complexity and time-consuming nature of treatments, un-palatability and side-effects of medications), it was clear that caregivers worked hard to overcome these day-to-day challenges and to deal with child resistance to treatments. Yet, carers reported that strict treatment adherence, which is expected by health professionals, could threaten their priorities around preserving family relationships and providing a ‘normal life’ for their child and any siblings.

Conclusions

Treatment adherence in long-term pediatric conditions is a complex issue which needs to be seen in the context of caregivers balancing the everyday needs of the child within everyday family life. Health professionals may be able to help caregivers respond positively to the challenge of treatment adherence for long-term conditions by simplifying treatment regimens to minimise impact on family life and being aware of difficulties around child resistance and supportive of strategies to attempt to overcome this. Caregivers would also welcome help with communicating with children about treatment goals.

【 授权许可】

   
2014 Santer et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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