BMC Infectious Diseases | |
The influence of chronic renal failure on the spectrum and antimicrobial susceptibility of uropathogens in community-acquired acute pyelonephritis presenting as a positive urine culture | |
Hark Rim1  Ho Sik Shin1  Yeon Soon Jung1  | |
[1] Department of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea | |
关键词: Antimicrobial Susceptibility; Chronic Renal Failure; Pyelonephritis; | |
Others : 1175747 DOI : 10.1186/1471-2334-11-102 |
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received in 2010-12-27, accepted in 2011-04-21, 发布年份 2011 | |
【 摘 要 】
Background
The role of chronic renal failure (CRF) in the antimicrobial resistance of uropathogens in patients with community-acquired acute pyelonephritis (APN) remains poorly understood.
Method
We performed a retrospective analysis of 502 adults (54 men, 448 women; mean age 61.7 ± 16.0 years, range 18-98 years) who were treated for community-acquired APN at Kosin University Gospel Hospital (Busan, Republic of Korea) during a ten-year period (January 2000 to December 2009). We evaluated the spectra and antimicrobial susceptibility profiles of uropathogens in CRF and non-CRF patients with community-acquired APN that presented as a positive urine culture.
Results
The 502 adult subjects were classified as either non-CRF APN patients (336 patients, 66.9%) or CRF APN patients (166 patients, 33.1%) according to their estimated glomerular filtration rate. No significant differences in the sensitivity of E. coli to a third cephalosporin, aminoglycoside (except gentamycin), or ciprofloxacin were observed between non-CRF and CRF patients.
Conclusions
In our series of patients with community-acquired APN that initially presented as a positive urine culture, CRF did not influence the isolation rates of different uropathogens or their patterns of susceptibility to antimicrobials.
【 授权许可】
2011 Jung et al; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
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20150428045058618.pdf | 164KB | download |
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